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神经调控技术: 重构神经元的新秩序

北京协和医院神经科2023级硕士研究生  郭雨婷

随着脑医学技术的飞速发展, 神经与精神疾病的诊疗正经历着前所未有的突破与革新, 因此 《协和医学杂志》本期重点选题方向定为"新技术引领的神经精神疾病诊疗进展"。如何在封面元素中展现"新技术"这一概念成为此次创作的重点与难点。

脑医学领域的新技术涵盖了脑机接口 (BCI)、经颅磁刺激(TMS)、脑深部电刺激 (DBS)、脊髓电刺激(SCS)等一大类神经调控前沿技术, 这些突破性技术推动着神经精神领域的诊疗范式正在发生深刻变革。经过深思熟虑, 画面主体决定采用交通枢纽的形象来反映神经元的工作状态, 蓝色为正常神经元, 灰色为异常神经元, 各种神经调控技术分布在神经元的关键节点, 在维持神经元这一"交通枢纽"的高效运转中发挥重要作用。画面上方, TMS可通过调节离子通道功能, 影响蛋白质的转录和翻译等分子机制, 恢复神经元正常的"交通秩序";画面中央,  BCI处于正常与异常神经元的交界处, 提示神经元的秩序化调控;画面左下方为SCS, 以黄色高铁代表接受刺激的脊髓, 比喻经刺激后的信号在高速传导;画面右上方为DBS, 大脑横跨在神经元的轴突上, 亦寓意信号的高效传导和神经元的精准调控。

TMS、BCI、SCS及DBS为神经与精神疾病的精准诊疗开辟了新路径, 这些技术不仅颠覆了传统治疗范式, 更推动了"脑-机交互"时代的临床转化, 将为人类脑健康与功能增强开辟全新可能。


Vol. 16, No. 2 29 03 2025
Chinese Bimonthly CN 11-5882/R ISSN 1674-9081
Category
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2025, 16(2): 292-299. DOI: 10.12290/xhyxzz.2024-1116
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2025, 16(2): 307-313. DOI: 10.12290/xhyxzz.2024-1003
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Application Effect of an Intelligent Medical Record Writing Assistant in Inpatient Medical Record Practice
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Risk of Circulating Tumor Cells and Clinical Blood Transfusion
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Effect of Erector Plane Muscle Block and Thoracic Paravertebral Block on Postoperative Analgesia in Patients with Breast Cancer: A Meta-analysis
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Advances and Challenges of miR-223 in Cardiovascular Disease
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Qualitative study on palliative care needs of peritoneal dialysis patients and caregivers
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Applications of Three-dimensional Facial Features in Disease Diagnosis and Treatment
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DOI: 10.12290/xhyxzz.2024-0717
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Summary of the evidence for ambulatory blood pressure monitoring in adults
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Microbial Contamination Control and Management of Human-derived Stem Cell Preparations and Related Regulations
CHEN Cuizhu, HUANG Changfa, LI Qian, WU Ze, CAO Chunran, WU Zhihong
DOI: 10.12290/xhyxzz.2024-0586
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Pathogenic Agents Causing Acute Respiratory Tract Infections in Beijing During Autumn and Winter of 2023 to 2024:A Study of 5,556 Patients from Peking Union Medical College Hospital
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Exploring the Mechanism and Intervention Strategies of Osteoporosis Based on the TLR4 Signaling Pathway
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Hematopoietic Engineering: The Current Status and Prospects of In Vitro Erythrocyte Production Technology
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DOI: 10.12290/xhyxzz.2024-0612
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Constructed the Global Health Policy and Management Evidence Clearinghouse to Facilitate Evidence-based Policymaking and Health Governance for Sustainable Development
TIAN Chen, YANG Shuihua, YANG Kehu, GE Long
DOI: 10.12290/xhyxzz.2024-0763
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Advances in Etiology of High Incidence of Thyroid Cancer in Women
TAN Meijuan, YANG Shijie, LIU Zhenzuan, LIU Yumeng, XU Xiequn
DOI: 10.12290/xhyxzz.2024-0525
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Radionuclide Drug Conjugates: China's 15-Year Research and Development Process and Latest Policy Support
LIU Dan, LI Xiuqi, LIU Shupeng, WU Xiaofei, YU Mengyang, WANG Hongyun
DOI: 10.12290/xhyxzz.2024-0577
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Requirements and Technical Aspects of Real-world Data Governance in China's Medical Standards and Guidelines
GUAN Xinmiao, ZHU Yanzi, LIU Hao, LUO Minjing, LIANG Changhao, CAO Feng, LIU Zhihan, ZHOU Jianguo, ZHANG Dong, FEI Yutong
DOI: 10.12290/xhyxzz.2024-0409
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Near-peer Learning in Neurology Residency Training on Electromyography
TAN Ying, HONG Yuehui, LI Jia, SHEN Dongchao, SHI Jiayu, YIN Hexiang, ZHOU Lixin, NI Jun, ZHU Yicheng
DOI: 10.12290/j.issn.1674-9081.2024-0350
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Research Progress on the Relationship Between Reproductive Tract Microbes and Tubal Pregnancy
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DOI: 10.12290/xhyxzz.2024-0297
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The Journey and Significance of Quality Control in Medical Safety for China's Plastic Surgery and Aesthetic Medicine Professions
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DOI: 10.12290/xhyxzz.2024-0487
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A Case Report of Mitochondrial Diabetes Mellitus Caused by Gross Deletion of Mitochondrial Gene and Literature Review
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DOI: 10.12290/xhyxzz.2024-0285
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Ulcerative Colitis Combined with Persistent Nausea and Vomiting During Pregnancy: A Case Report
WEI Wei, LI Rui, ZHANG Yuping, LIU Yanping
DOI: 10.12290/j.issn.1674-9081.2023-0535
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Transient Peripheral Carotid Inflammation Syndrome Diagnosed by Contrastenhanced Ultrasound: A Case Report
PAN Chunlei, WANG Ying, WANG Yahong, ZHANG Li, GE Zhitong, CHEN Yu, CAI Sheng, WANG Hongyan, YANG Xiao, LI Jianchu
DOI: 10.12290/xhyxzz.2024-0124
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Establishment of a LASSO Regression-Based Risk Prediction Model for Early Recurrence of SiewertⅡ/Ⅲ Adenocarcinoma of Esophagogastric Junction Post-Surgery
ZHANG Zuyu, WEI Hong, LIU Qian, WANG Yaoqiang, FAN Xueyan, LUO Ruiying, LUO Changjiang
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Esketamine Improves Working Memory Impairment in Neuropathic Mice Through Hippocampal BDNF-TrkB Pathway
JIANG Yubin, WANG Xingming, ZHANG Yue, ZHOU Zhiqiang, YANG Jianjun
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由中国科协、教育部、科技部、财政部、国家新闻出版署、中国科学院、中国工程院联合实施的“中国科技期刊卓越行动计划二期项目”结果于11月28日正式公布,《协和医学杂志》在激烈角逐中脱颖而出,入选“中文梯队期刊”。

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经主动申报和严格评审,《协和医学杂志》于2024年12月20日正式被美国化学文摘社(Chemical Abstracts Service,CAS)数据库收录!

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CAS数据库是美国化学会(American Chemical Society,ACS)的分支机构,创立于1907年,收录了全球数千种包括化学、生命科学等领域的期刊,为全球科研人员提供化学、生物医学等领域的专业信息服务。CAS也是全球化学、制药公司、大学、政府部门和专利机构公认的最大、最全面、最具权威的数据库。

此次被CSA数据库收录,是继期刊被DOAJ、Scopus、WPRIM数据库收录后,进入的又一个重要国际数据库,标志着《协和医学杂志》的学术影响力得到更多国际数据库肯定,同时为国内外学者提供了更加广阔的交流平台!

 

 

 


为推动传统期刊与新媒体融合,构建“内容+技术+渠道”立体化传播格局,“医学期刊新媒体传播共同体”正式启动。《协和医学杂志》成为医学期刊新媒体传播共同体首批合作期刊。

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医学期刊新媒体传播共同体的加入,标志着《协和医学杂志》新媒体传播未来将肩负更多使命与责任,我们将以更高的专业标准打造权威医学知识传播平台,通过创新融媒体形式深化医学科普内容创作;强化与共同体成员的协同联动,推动行业传播新的发展范式,为健康中国战略实施持续贡献智慧力量。

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学术诚信是学术研究的基石,是学术界应共同遵守的基本原则。为充分利用新媒体传播渠道,搭建集学术诚信宣传、教育、监督于一体的平台,中国高校科技期刊研究会发起,联合“观见学术”公众号,建立“学术诚信与出版新媒体矩阵”。《协和医学杂志》新媒体平台成为首批“学术诚信与出版新媒体矩阵”成员单位。

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