TAN Meijuan, YANG Shijie, LIU Zhenzuan, LIU Yumeng, XU Xiequn. Advances in Etiology of High Incidence of Thyroid Cancer in Women[J]. Medical Journal of Peking Union Medical College Hospital. DOI: 10.12290/xhyxzz.2024-0525
Citation:
TAN Meijuan, YANG Shijie, LIU Zhenzuan, LIU Yumeng, XU Xiequn. Advances in Etiology of High Incidence of Thyroid Cancer in Women[J]. Medical Journal of Peking Union Medical College Hospital. DOI: 10.12290/xhyxzz.2024-0525
TAN Meijuan, YANG Shijie, LIU Zhenzuan, LIU Yumeng, XU Xiequn. Advances in Etiology of High Incidence of Thyroid Cancer in Women[J]. Medical Journal of Peking Union Medical College Hospital. DOI: 10.12290/xhyxzz.2024-0525
Citation:
TAN Meijuan, YANG Shijie, LIU Zhenzuan, LIU Yumeng, XU Xiequn. Advances in Etiology of High Incidence of Thyroid Cancer in Women[J]. Medical Journal of Peking Union Medical College Hospital. DOI: 10.12290/xhyxzz.2024-0525
1 Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China;
2 Cancer Hospital Chinese Academy of Medical Science, Beijing 100029, China;
3 Department of Histology and Embryology, School of Medicine, Shihezi University, Shihezi, Xinjiang Uygur Autonomous Regions 832003, China
Funds:
Beijing Municipal Natural Science Foundation (7222127); National Natural Science Foundation of China (32071436)
Thyroid cancer is the only non reproductive tumor that mainly occurs in women. The morbidity rate of female thyroid cancer is three times higher than that of male thyroid cancer. However, the existing studies have not systematically summarized the factors that contribute to the high incidence of thyroid cancer in women. This paper reviews all the literatures that mention the high incidence of thyroid cancer in women, and sorts out the main reasons, such as estrogen, obesity, reproductive factors, oxidation antioxidant system imbalance, X chromosome, etc., which are the main reasons for the current research finding that the incidence rate of thyroid cancer in women is higher than that in men. This paper makes a vivid graphic analysis and summary of the reasons, providing a research direction for future researchers to research on gender duality of thyroid cancer, and providing a certain reference for the clinical diagnosis and treatment of gender differences in thyroid cancer.