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Volume 15 Issue 1
Jan.  2024
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XU Jinhui, YUE Hongmei, LIU Miaomiao, LI Yating, WU Xingdong, ZHU Haobin. Role of Neutrophil Extracellular Traps in Chronic Obstructive Pulmonary Disease[J]. Medical Journal of Peking Union Medical College Hospital, 2024, 15(1): 153-159. DOI: 10.12290/xhyxzz.2023-0396
Citation: XU Jinhui, YUE Hongmei, LIU Miaomiao, LI Yating, WU Xingdong, ZHU Haobin. Role of Neutrophil Extracellular Traps in Chronic Obstructive Pulmonary Disease[J]. Medical Journal of Peking Union Medical College Hospital, 2024, 15(1): 153-159. DOI: 10.12290/xhyxzz.2023-0396
shu

Role of Neutrophil Extracellular Traps in Chronic Obstructive Pulmonary Disease

  • 1.

    The First Clinical College of Medicine, Lanzhou University, Lanzhou 730000, China

  • 2.

    Department of Respiratory and Critical Care Medicine, The First Hospital of Lanzhou University, Lanzhou 730000, China

Funds: 

Gansu Provincial Science and Technology Program 22ZD1FA001

More Information
  • Corresponding author:

    YUE Hongmei, E-mail: yuehongmei@sina.com

  • Received Date: August 23, 2023
  • Accepted Date: September 17, 2023
  • Available Online: January 23, 2024
  • Issue Publish Date: January 29, 2024
    Graphical Abstract
    • Abstract
  • Chronic obstructive pulmonary disease (COPD), a respiratory disease characterized by inflammation due to neutrophil infiltration, has become the third leading cause of death worldwide. After the occurrence of COPD, the persistent accumulation of neutrophils can promote the excessive formation of neutrophil extracellular traps (NETs), which plays an important role in local capture and clearance of pathogens, rapid control of infection, and immune regulation. This article mainly introduces the mechanism of COPD occurrence and NETs formation as well as the research progress of NETs in COPD, and summarizes the relevant drug targets for COPD treatment based on NETs, aiming to provide a reference for further research.
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    • References (52)
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