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Volume 13 Issue 5
Sep.  2022
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Article Navigation >  Medical Journal of Peking Union Medical College Hospital  > 2022  >  13(5): 725-731
ZHAO Xinyue, HU Xiaomin, ZHANG Shuyang. Gut Microbiome and Cardiovascular Health: Heart and Gut are Inextricably Linked[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(5): 725-731. doi: 10.12290/xhyxzz.2022-0444
Citation: ZHAO Xinyue, HU Xiaomin, ZHANG Shuyang. Gut Microbiome and Cardiovascular Health: Heart and Gut are Inextricably Linked[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(5): 725-731. doi: 10.12290/xhyxzz.2022-0444
shu

Gut Microbiome and Cardiovascular Health: Heart and Gut are Inextricably Linked

doi: 10.12290/xhyxzz.2022-0444
  • 1.

    Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 2.

    State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 3.

    Medical Research Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

Funds:

National Natural Science Foundation 8217022134

Beijing Natural Science Foundation 7202152

National High Level Hospital Clinical Research Funding 2022-PUMCH-A-026

More Information
  • Corresponding author: HU Xiaomin, E-mail: huxiaomin2015@163.com; ZHANG Shuyang, E-mail: shuyangzhang103@163.com
  • Received Date: 2022-08-12
  • Accepted Date: 2022-08-24
    • Available Online: 2022-09-07
  • Publish Date: 2022-09-30
    Abstract
  • In recent years, with the progress of multi-omics and next-generation sequencing technology, the association between gut microbiome and cardiovascular diseases has attracted great attention around the world. Gut microbiota, as a "microbial organ", directly regulates the host's health status through lipopolysaccharide, metabolites like trimethylamine oxide and short-chain fatty acids, and affects the host's immunity through bacteria and their products. "Gut-heart axis" may be a breakthrough in the prevention and treatment of cardiovascular diseases. The paper briefly discusses the relationship between gut microbiome and cardiovascular diseases, the possible ways in which gut microbes affect cardiovascular health, and the regulation of gut microbiota by various factors.
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