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Volume 14 Issue 3
May  2023
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TIAN Xinping, ZHAO Jiuliang, LI Mengtao, SONG Yijun, LIU Juntao, ZENG Xiaofeng. Interpretation on the 2022 Chinese Guideline for the Management of Pregnancy and Reproduction in Patients with Systemic Lupus Erythematous[J]. Medical Journal of Peking Union Medical College Hospital, 2023, 14(3): 504-513. DOI: 10.12290/xhyxzz.2023-0119
Citation: TIAN Xinping, ZHAO Jiuliang, LI Mengtao, SONG Yijun, LIU Juntao, ZENG Xiaofeng. Interpretation on the 2022 Chinese Guideline for the Management of Pregnancy and Reproduction in Patients with Systemic Lupus Erythematous[J]. Medical Journal of Peking Union Medical College Hospital, 2023, 14(3): 504-513. DOI: 10.12290/xhyxzz.2023-0119
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Interpretation on the 2022 Chinese Guideline for the Management of Pregnancy and Reproduction in Patients with Systemic Lupus Erythematous

  • 1.

    Department of Rheumatology and Clinical Immunology, National Clinical Research Center for Dermatologic and Immunologic Diseases, Ministry of Science & Technology, State Key Laboratory of Complex Severe and Rare Diseases, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 2.

    Research Center for Obstetrics and Gynecology National Clinical Research Center for Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

Funds: 

National Key Research and Development Program of China 2021YFC2501300

National High Level Hospital Clinical Research Funding 2022-PUMCH-B-013

National High Level Hospital Clinical Research Funding 2022-PUMCH-C-002

National High Level Hospital Clinical Research Funding 2022-PUMCH-D-009

Beijing Municipal Science and Technology Commission Z201100005520022

Beijing Municipal Science and Technology Commission Z201100005520023

Beijing Municipal Science and Technology Commission Z201100005520025

Beijing Municipal Science and Technology Commission Z201100005520026

Beijing Municipal Science and Technology Commission Z201100005520027

CAMS Innovation Fund for Medical Sciences 2021-I2M-1-005

More Information
  • Corresponding author:

    ZENG Xiaofeng, E-mail: zengxfpumc@163.com

  • Received Date: March 09, 2023
  • Accepted Date: April 06, 2023
  • Available Online: April 27, 2023
  • Issue Publish Date: May 29, 2023
    Graphical Abstract
    • Abstract
  • Systemic lupus erythematosus (SLE) is an autoimmune disease most prevalent in child-bearing young women. With the progress of treatment, the survival rate of SLE patients has been remarkably improved. Reproduction management of SLE patients has become one of the most important parts of SLE patients management. However, due to the complicated inter-reaction between SLE disease and the related concurrent problems, reproduction management of SLE patients remains a big challenge. Led and guided by the National Clinical Research Center for Dermatologic and Immunologic Diseases, the National Clinical Research Center for Obstetrics and Gynecology, Chinese Systemic Lupus Erythematosus Treatment and Research Group and Chinese Research Committee of Pregnancy and Reproduction in Autoimmune Rheumatic Diseases, the first guideline dedicated to the management of pregnancy and reproduction in patients with systemic lupus erythematous has been developed. This guideline is composed of 13 evidence-based recommendations, including pre-pregnant preparation (pre-pregnant consultation, risk assessment, indications and contraindications for pregnancy and the choices of assisted reproduction technology), monitoring and treatment strategy during pregnancy, monitoring and complications identification and management of the fetus, and recommendations for disease follow-up after delivery and feeding of the neonates. These recommendations, covering the whole process of pregnancy of SLE patients, are aimed to improve the success rate of pregnancy of SLE patients and decrease the morbidity and mortality of SLE patients and their fetus.
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    • References (34)
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