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抗肿瘤药物安全管理系统的建立与运行效果分析

孙雯娟 邹羽真 张凡 张路 赵林 白春梅 张锋 徐燕 茅枫 李菁 顾宇 范欣荣 王孟昭 周道斌 张占杰 赵彬 杜小莉 张波 孙学勤 龙笑 常青 胡冰水 潘慧 吴文铭

孙雯娟, 邹羽真, 张凡, 张路, 赵林, 白春梅, 张锋, 徐燕, 茅枫, 李菁, 顾宇, 范欣荣, 王孟昭, 周道斌, 张占杰, 赵彬, 杜小莉, 张波, 孙学勤, 龙笑, 常青, 胡冰水, 潘慧, 吴文铭. 抗肿瘤药物安全管理系统的建立与运行效果分析[J]. 协和医学杂志. doi: 10.12290/xhyxzz.2021-0704
引用本文: 孙雯娟, 邹羽真, 张凡, 张路, 赵林, 白春梅, 张锋, 徐燕, 茅枫, 李菁, 顾宇, 范欣荣, 王孟昭, 周道斌, 张占杰, 赵彬, 杜小莉, 张波, 孙学勤, 龙笑, 常青, 胡冰水, 潘慧, 吴文铭. 抗肿瘤药物安全管理系统的建立与运行效果分析[J]. 协和医学杂志. doi: 10.12290/xhyxzz.2021-0704
SUN Wenjuan, ZOU Yuzhen, ZHANG Fan, ZHANG Lu, ZHAO Lin, BAI Chunmei, ZHANG Feng, XU Yan, MAO Feng, LI Jing, GU Yu, FAN Xinrong, WANG Mengzhao, ZHOU Daobin, ZHANG Zhanjie, ZHAO Bin, DU Xiaoli, ZHANG Bo, SUN Xueqin, LONG Xiao, CHANG Qing, HU Bingshui, PAN Hui, WU Wenming. Design and Operation Effect Analysis of Antitumor Drug Safety Management System[J]. Medical Journal of Peking Union Medical College Hospital. doi: 10.12290/xhyxzz.2021-0704
Citation: SUN Wenjuan, ZOU Yuzhen, ZHANG Fan, ZHANG Lu, ZHAO Lin, BAI Chunmei, ZHANG Feng, XU Yan, MAO Feng, LI Jing, GU Yu, FAN Xinrong, WANG Mengzhao, ZHOU Daobin, ZHANG Zhanjie, ZHAO Bin, DU Xiaoli, ZHANG Bo, SUN Xueqin, LONG Xiao, CHANG Qing, HU Bingshui, PAN Hui, WU Wenming. Design and Operation Effect Analysis of Antitumor Drug Safety Management System[J]. Medical Journal of Peking Union Medical College Hospital. doi: 10.12290/xhyxzz.2021-0704

抗肿瘤药物安全管理系统的建立与运行效果分析

doi: 10.12290/xhyxzz.2021-0704
详细信息
    通讯作者:

    赵彬,E-mail:zhaobin@pumch.cn

  • 中图分类号: R979.1;R730.53

Design and Operation Effect Analysis of Antitumor Drug Safety Management System

  • 摘要: 目的 设计抗肿瘤药物安全管理系统,从处方源头拦截超剂量医嘱,保障抗 肿瘤药物临床应用的安全性。 方法 制订某三甲医院88 种抗肿瘤药物阈值拦截/警示策略, 建立抗肿瘤药物安全管理系统,对超剂量抗肿瘤药物医嘱进行拦截/警示。调取2021 年1 月 —2021 年6 月抗肿瘤药物安全管理系统中的拦截/警示数据并进行统计分析。 结果 抗肿 瘤药物安全管理系统共拦截/警示医嘱665 条,其中触发拦截功能的医嘱共642 条(96.54%), 触发警示功能的医嘱共23 条(3.46%);拦截/警示药品以口服片剂为主(494,74.29%); 被拦截医嘱中,频次错误占比最高(64.22%),其次为途径错误(11.73%)和剂量错误(9.92%)。 拦截超剂量医嘱564 条,涉及抗肿瘤药物28 种;拦截次数最多的抗肿瘤药物为甲氨蝶呤片, 平均超剂量7 倍;注射用培美曲塞二钠平均超剂量倍数排名第1,平均超剂量1000 倍。拦 截超途径医嘱78 条,涉及抗肿瘤药物5 种。 结论 抗肿瘤药物安全管理系统从处方环节 杜绝了医嘱超剂量用药错误,切实保障了抗肿瘤药物的用药安全。
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出版历程
  • 收稿日期:  2021-10-21
  • 网络出版日期:  2022-03-09

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