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Volume 13 Issue 3
May  2022
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Article Navigation >  Medical Journal of Peking Union Medical College Hospital  > 2022  >  13(3): 370-376
LI Zhujun, WANG Chenyu, LONG Xiao. Application of Mesenchymal Stem Cells in Plastic and Cosmetic Surgery[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(3): 370-376. doi: 10.12290/xhyxzz.2022-0036
Citation: LI Zhujun, WANG Chenyu, LONG Xiao. Application of Mesenchymal Stem Cells in Plastic and Cosmetic Surgery[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(3): 370-376. doi: 10.12290/xhyxzz.2022-0036
shu

Application of Mesenchymal Stem Cells in Plastic and Cosmetic Surgery

doi: 10.12290/xhyxzz.2022-0036
  • 1.

    Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 2.

    State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

  • 3.

    Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China

Funds:

National Key R & D Program of China 2020YFE0201600

CAMS Innovation Fund for Medical Sciences 2020-I2M-C & T-A-004

More Information
  • Corresponding author: LONG Xiao, E-mail: pumclongxiao@126.com
  • Received Date: 2022-01-24
  • Accepted Date: 2022-04-06
    • Available Online: 2022-04-19
  • Publish Date: 2022-05-30
    Abstract
  • Mesenchymal stem cells(MSCs) are adult stem cells that possess the ability of self-renewal and multi-lineage differentiation. They can be found in multiple tissue types, including adipose tissue, bone marrow and umbilical cord. MSCs can exert the effects of tissue repair, angiogenesis, immunoregulation, and anti-fibrosis through differentiation or paracrine function. Promising therapeutic effects of MSCs on skin aging, alopecia, tissue regeneration, wound healing, and anti-fibrosis have been observed. In general, MSCs exhibit favorable therapeutic effects and safety, but scrutinized research and clinical trials are still needed to reveal the mechanism of action as well as long-term efficacy and safety.
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