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Volume 11 Issue 3
May  2020
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Han-xiao YOU, Meng-tao LI, Feng-chun ZHANG, Xiao-feng ZENG, Chao-jun HU. Autoantibodies Involved in Neuropsychiatric Systemic Lupus Erythematosus and Its Diagnostic Value[J]. Medical Journal of Peking Union Medical College Hospital, 2020, 11(3): 264-269. DOI: 10.3969/j.issn.1674-9081.20200043
Citation: Han-xiao YOU, Meng-tao LI, Feng-chun ZHANG, Xiao-feng ZENG, Chao-jun HU. Autoantibodies Involved in Neuropsychiatric Systemic Lupus Erythematosus and Its Diagnostic Value[J]. Medical Journal of Peking Union Medical College Hospital, 2020, 11(3): 264-269. DOI: 10.3969/j.issn.1674-9081.20200043
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Autoantibodies Involved in Neuropsychiatric Systemic Lupus Erythematosus and Its Diagnostic Value

  • Department of Rheumatology and Clinical Immunology, National Clinical Research Center for Dermatologic and Immunologic Diseases, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

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  • Corresponding author:

    HU Chao-jun  Tel: 86-10-69159966, E-mail:huchaojun818@qq.com

  • Received Date: February 22, 2020
  • Issue Publish Date: May 29, 2020
    Graphical Abstract
    • Abstract
  • Neuropsychiatric systemic lupus erythematosus (NPSLE) is a group of severe complications with a poor prognosis and high mortality caused by systemic lupus erythematosus (SLE). Its lesions involve the nervous system and cause neurological and/or psychiatric symptoms. Unique autoantibodies detected in the serum or cerebrospinal fluid of patients with NPSLE are associated with the presence of neuropsychiatric disorders. The prevalence of NPSLE ranges from 17% to 75% in SLE. This article reviewed the latest progress and focused on the current state of knowledge and the potential clinical value of anti-ribosomal P antibody, antiphospholipid antibody, anti-neuronal antibody, and other related antibodies in NPSLE with central nervous involvement.
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    • References (44)
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