Email Alert RSS
Volume 10 Issue 5
Turn off MathJax
Article Contents
Abstract
References
Related Articles
Zhen WANG, Zhong-wei CHENG, Tai-bo CHEN, Peng GAO, Quan FANG. Relationship between Non-sustained Ventricular Tachycardia before Implantation and Appropriate Therapy in Patients with Implantable Cardioverter Defibrillator for Primary Prevention of Sudden Cardiac Death[J]. Medical Journal of Peking Union Medical College Hospital, 2019, 10(5): 494-498. DOI: 10.3969/j.issn.1674-9081.2019.05.012
Citation: Zhen WANG, Zhong-wei CHENG, Tai-bo CHEN, Peng GAO, Quan FANG. Relationship between Non-sustained Ventricular Tachycardia before Implantation and Appropriate Therapy in Patients with Implantable Cardioverter Defibrillator for Primary Prevention of Sudden Cardiac Death[J]. Medical Journal of Peking Union Medical College Hospital, 2019, 10(5): 494-498. DOI: 10.3969/j.issn.1674-9081.2019.05.012
shu

Relationship between Non-sustained Ventricular Tachycardia before Implantation and Appropriate Therapy in Patients with Implantable Cardioverter Defibrillator for Primary Prevention of Sudden Cardiac Death

  • Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

More Information
  • Corresponding author:

    FANG Quan Tel: 86-10-69155069, E-mail:13801371164@163.com

  • Received Date: March 03, 2019
  • Issue Publish Date: September 29, 2019
    Graphical Abstract
    • Abstract
  •   Objective  The aim of this study was to explore the relationship between non-sustained ventricular tachycardia (NSVT) recorded by Holter before implantation and appropriate therapy in patients with implantable cardioverter defibrillator (ICD) for primary prevention of sudden cardiac death.
      Methods  A single-center retrospective cohort study was conducted. Consecutive inpatients who received ICD for primary prevention and finished Holter examination from January 2006 to December 2017 in Peking Union Medical College Hospital were enrolled. According to the results of Holter, the patients were divided into the NSVT group and the non-NSVT group. Clinic or telephone follow-ups were conducted until August 2018; the follow-up events included all-cause death, shock therapy, and anti-tachycardia pacing (ATP).
      Results  Sixty patients meeting the inclusive and exclusive criteria were enrolled in this study. Median follow-up of all patients was 37 (14-61) months. Kaplan-Meier curve and Log-Rank test showed that there was no significant difference in mortality between the NSVT and the non-NSVT group (P=0.108), while the NSVT group had a significantly higher rate of appropriate therapy (P=0.033). Multivariate competitive risk regression analysis indicated that NSVT and left ventricular ejection fraction were independently correlated with the ICD appropriate therapy (NSVT: HR=5.099, 95% CI:1.399-18.588, P=0.014; left ventricular ejection fraction: HR=1.077, 95% CI:1.013-1.145, P=0.018).
      Conclusion  NSVT in patients with ICD implantation for primary prevention suggests an increased risk of receiving appropriate therapy.
    • FullText(HTML)
    • References (20)
  • [1]
    Kostis JB, McCrone K, Moreyra AE, et al. Premature ventricular complexes in the absence of identifiable heart disease[J]. Circulation, 1981, 63:1351-1356. DOI: 10.1161/01.CIR.63.6.1351
    [2]
    Camm AJ, Evans KE, Ward DE, et al. The rhythm of the heart in active elderly subjects[J]. Am Heart J, 1980, 99:598-603. DOI: 10.1016/0002-8703(80)90733-4
    [3]
    Meinertz T, Hofmann T, Kasper W, et al. Significance of ventricular arrhythmias in idiopathic dilated cardiomyopathy[J]. Am J Cardiol, 1984, 53:902-907. DOI: 10.1016/0002-9149(84)90522-8
    [4]
    Massing MW, Simpson RJ, Rautaharju PM, et al. Usefulness of ventricular premature complexes to predict coronary heart disease events and mortality (from the Atherosclerosis Risk In Communities cohort)[J]. Am J Cardiol, 2006, 98:1609-1612. DOI: 10.1016/j.amjcard.2006.06.061
    [5]
    Agarwal SK, Heiss G, Rautaharju PM, et al. Premature ventricular complexes and the risk of incident stroke:the Atherosclerosis Risk In Communities (ARIC) Study[J]. Stroke, 2010, 41:588-593. DOI: 10.1161/STROKEAHA.109.567800
    [6]
    Cheriyath P, He F, Peters I, et al. Relation of atrial and/or ventricular premature complexes on a two-minute rhythm strip to the risk of sudden cardiac death (the Atherosclerosis Risk in Communities[ARIC] study)[J]. Am J Cardiol, 2011, 107:151-155. DOI: 10.1016/j.amjcard.2010.09.002
    [7]
    Lee V, Hemingway H, Harb R, et al. The prognostic significance of premature ventricular complexes in adults without clinically apparent heart disease:a meta-analysis and systematic review[J]. Heart, 2012, 98:1290-1298. DOI: 10.1136/heartjnl-2012-302005
    [8]
    Bergau L, Willems R, Sprenkeler DJ, et al. Differential multivariable risk prediction of appropriate shock versus competing mortality-A prospective cohort study to estimate benefits from ICD therapy[J]. Int J Cardiol, 2018, 272:102-107. DOI: 10.1016/j.ijcard.2018.06.103
    [9]
    Killu AM, Mazo A, Grupper A, et al. Super-response to cardiac resynchronization therapy reduces appropriate implantable cardioverter defibrillator therapy[J]. Europace, 2018, 20:1303-1311. DOI: 10.1093/europace/eux235
    [10]
    Teerlink JR, Jalaluddin M, Anderson S, et al. Ambulatory ventricular arrhythmias in patients with heart failure do not specifically predict an increased risk of sudden death. PROMISE (Prospective Randomized Milrinone Survival Evaluation) Investigators[J]. Circulation, 2000, 101:40-46. DOI: 10.1161/01.CIR.101.1.40
    [11]
    Yokoshiki H, Shimizu A, Mitsuhashi T, et al. Prognostic significance of nonsustained ventricular tachycardia in patients receiving cardiac resynchronization therapy for primary preven-tion:Analysis of the Japan cardiac device treatment registry database[J]. J Arrhythm, 2018, 34:139-147. DOI: 10.1002/joa3.12023
    [12]
    Chen J, Johnson G, Hellkamp AS, et al. Rapid-rate nonsustained ventricular tachycardia found on implantable cardioverter-defibrillator interrogation:relationship to outcomes in the SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial)[J]. J Am Coll Cardiol, 2013, 61:2161-2168. DOI: 10.1016/j.jacc.2013.02.046
    [13]
    Jiménez-Candil J, Hernández J, Perdiguero P, et al. Prognostic significance of nonsustained ventricular tachycardia episodes occurring early after implantable cardioverter-defibrillator implantation among patients with left ventricular dysfunction[J]. Am J Cardiol, 2016, 118:1503-1510. DOI: 10.1016/j.amjcard.2016.08.015
    [14]
    Lee DS, Hardy J, Yee R, et al. Clinical risk stratification for primary prevention implantable cardioverter defibrillators[J]. Circ Heart Fail, 2015, 8:927-937. DOI: 10.1161/CIRCHEARTFAILURE.115.002414
    [15]
    Zhou Y, Zhao S, Chen K, et al. Predictive value of rapid-rate non-sustained ventricular tachycardia in the occurrence of appropriate implantable cardioverter-defibrillator therapy[J]. J Interv Card Electrophysiol, 2019.doi: 10.1007/s10840-019-00557-4.[Epub ahead of print].
    [16]
    Koller MT, Schaer B, Wolbers M, et al. Death without prior appropriate implantable cardioverter-defibrillator therapy:a competing risk study[J]. Circulation, 2008, 117:1918-1926. DOI: 10.1161/CIRCULATIONAHA.107.742155
    [17]
    Sticherling C, Arendacka B, Svendsen JH, et al. Sex differences in outcomes of primary prevention implantable cardioverter-defibrillator therapy:combined registry data from eleven European countries[J]. Europace, 2018, 20:963-970. DOI: 10.1093/europace/eux176
    [18]
    Seegers J, Conen D, Jung K, et al. Sex difference in appropriate shocks but not mortality during long-term follow-up in patients with implantable cardioverter-defibrillators[J]. Europace, 2016, 18:1194-1202. DOI: 10.1093/europace/euv361
    [19]
    van der Heijden AC, Thijssen J, Borleffs CJ, et al. Gender-specific differences in clinical outcome of primary prevention implantable cardioverter defibrillator recipients[J]. Heart, 2013, 99:1244-1249. DOI: 10.1136/heartjnl-2013-304013
    [20]
    van Rees JB, Borleffs CJ, van Welsenes GH, et al. Clinical prediction model for death prior to appropriate therapy in primary prevention implantable cardioverter defibrillator patients with ischaemic heart disease:the FADES risk score[J]. Heart, 2012, 98:872-877. DOI: 10.1136/heartjnl-2011-300632
    • Related Articles

  • Related Articles

    [1]YAN Xinchun, HUO Li. Evaluation of Von Hippel-Lindau Syndrome Through Novel Small Molecular Tracer 68Ga-NY104 PET/CT Imaging[J]. Medical Journal of Peking Union Medical College Hospital, 2024, 15(4): 911-915. DOI: 10.12290/xhyxzz.2024-0216
    [2]ZHANG Lu, LI Jian. Castleman Disease in China: State-of-the-art Technology Before the Era of IL-6 Targeted Therapy[J]. Medical Journal of Peking Union Medical College Hospital, 2023, 14(5): 911-914. DOI: 10.12290/xhyxzz.2023-0227
    [3]DUAN Anqi, LUO Qin, ZHAO Zhihui, ZHAO Qing, LIU Zhihong. Right Ventricular-pulmonary Arterial Coupling in Pulmonary Hypertension: Application Advances[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(6): 1051-1056. DOI: 10.12290/xhyxzz.2021-0797
    [4]ZHAO Zhe, TANG Yan, ZHOU Jingya, CHEN Xiaoguang, ZHANG Lei, CHEN Limeng, YUAN Tao. Analysis of Clinical Manifestations and Drug Therapies of Gitelman Syndrome[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(2): 277-286. DOI: 10.12290/xhyxzz.2021-0180
    [5]Ying XU, Ya-li XU, Zhe WANG, Yan LIN, Chang-jun WANG, Qiang SUN. Menopausal Hormone Therapy Increases the Risk of Breast Cancer:Interpretation on an Article Published in the Lancet Sep. 2019[J]. Medical Journal of Peking Union Medical College Hospital, 2020, 11(5): 621-625. DOI: 10.3969/j.issn.1674-9081.2020.05.020
    [6]Beyond the NICU: Comprehensive Care of the High-risk Infant(2015)[J]. Medical Journal of Peking Union Medical College Hospital, 2016, 7(6): 449-449.
    [8]Ming-sheng MA, Xü-de ZHANG, Min WEI, Shi-min ZHAO, Zheng-qing QIU. Efficacy of Low Dose Corticosteroid Therapy in Duchenne Muscular Dystrophy[J]. Medical Journal of Peking Union Medical College Hospital, 2014, 5(4): 384-388. DOI: 10.3969/j.issn.1674-9081.2014.04.006
    [9]Ya-gang ZUO, Hong-wei WANG, Jia-bi WANG. Dual-wavelength Laser with 595 nm and 1064 nm Combination for Resistant Port-wine Stains[J]. Medical Journal of Peking Union Medical College Hospital, 2012, 3(4): 386-389. DOI: 10.3969/j.issn.1674-9081.2012.04.005
    [10]Jie LIU, Yue-ping ZENG, Chun-xia HE, Qin LONG, Hong-zhong JIN, Qiu-ning SUN. Corticosteroids plus Intravenous Immunoglobulin in the Treatment of 7 Cases with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis[J]. Medical Journal of Peking Union Medical College Hospital, 2012, 3(4): 381-385. DOI: 10.3969/j.issn.1674-9081.2012.04.004

  • Cited by

    Periodical cited type(16)

    1. 杨叶，杨晨，李迎君. 健康中国战略背景下临床流行病学教学改革思路. 科技风. 2024(10): 125-127 .
    2. 陈海燕，杨丽，李红俊，李晓霞，杨尹，王静，张国美，刘蜻蜻. 以精准诊断为导向的超声医学住培教学实践. 中国继续医学教育. 2023(08): 178-182 .
    3. 李长玲，李方，姚小美，褚传莲，张涌，王滨. 案例教学结合翻转课堂应用于临床流行病学本科生教学的效果研究. 中国社区医师. 2023(12): 164-166 .
    4. 贾福运，高晟玮，张茜，徐强. 中医药临床疗效评价方法研究进展. 时珍国医国药. 2023(07): 1720-1723 .
    5. 胡付兰，胡东生，张明. 混合教学模式在临床流行病学教学中的实践应用——以微课、超星学习通、TBL与LBL相结合为例. 教育教学论坛. 2023(34): 121-124 .
    6. 朱金明. 新时代背景下胃肠外科青年医师培养的几点思考. 中华消化病与影像杂志(电子版). 2022(01): 52-54 .
    7. 赵天易，雒琳，何丽云，吕晓颖，宫嫚，李筠，李少红，李洪皎，刘佳，刘保延，艾艳珂. 多源异构数据整合在中医药真实世界临床研究中的应用及展望. 世界中医药. 2022(05): 614-619 .
    8. 车贺宾，徐洪丽. 临床数据处理流程规范构建. 医学信息学杂志. 2022(03): 52-55 .
    9. 李健爽，郭艳萍，张涛，刘加勇，李欣，马翠. 翻转课堂联合案例分析教学法在流行病学教学中的应用. 继续医学教育. 2022(08): 24-27 .
    10. 李雪航，武文君，马玉，宋扬，王盛书，王建华，贾王平，韩珂，刘少华，陈仕敏，何耀，刘淼. 对医学研究生《临床流行病学》课程教学的满意度及影响因素分析. 转化医学杂志. 2022(06): 337-340+359 .
    11. 陆玉林，骆文，陆丽明. 开展真实世界中医药临床研究的机遇与挑战. 中华中医药杂志. 2021(08): 4443-4446 .
    12. 王倩，陶宁，阿提开木·吾布力，培尔顿·米吉提，戴江红. 基于雨课堂的临床流行病学教学改革与实践. 中国医学教育技术. 2020(02): 206-208+213 .
    13. 金倩莹，李星明. 流行病学方法在医学研究中的应用概述. 北京医学. 2020(05): 444-451 .
    14. 符宇，邵明义，赵瑞霞，吴明慧，远佳瑶，余海滨，崔伟峰. 基于中医证据的中医临床疗效评价方法探讨. 中医杂志. 2020(13): 1124-1129 .
    15. 吴东，刘晓清. David Sackett:循证医学之父. 协和医学杂志. 2020(04): 449-452 . 本站查看
    16. 熊益权，谭婧. 在高等医学院校临床科研培训课程中开设真实世界数据与研究模块的探讨. 成都中医药大学学报(教育科学版). 2020(02): 36-39 .

    Other cited types(4)

Catalog

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (462) PDF downloads (94) Cited by(20)
    Related
    Address：Room 302,Third Floor,Building 7, No. 1 Shuaifuyuan, Wangfujing, Dongcheng District, Beijing 100730, China
    Tel：010-69154261/4262
    E - mail：medj@pumch.cn mjpumch@126.com
    Copyright of website：Editorial Office of Medical Journal of Peking Union Medical College Hospital

      Supported by: Beijing Renhe Information Technology Co., Ltd.  Baidu Analytics

      /

      DownLoad:  Full-Size Img  PowerPoint
      Return
      Return
      x Close Forever Close