Volume 12 Issue 4
Jul.  2021
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Article Contents
ZHOU Menglan, WANG Yao, XU Yingchun, WU Jie, YI 1jie, SUN Fangyan, CHEN Yu. Be on the Alert for Norovirus Epidemics and Outbreaks[J]. Medical Journal of Peking Union Medical College Hospital, 2021, 12(4): 433-437. doi: 10.12290/xhyxzz.2020-0091
Citation: ZHOU Menglan, WANG Yao, XU Yingchun, WU Jie, YI 1jie, SUN Fangyan, CHEN Yu. Be on the Alert for Norovirus Epidemics and Outbreaks[J]. Medical Journal of Peking Union Medical College Hospital, 2021, 12(4): 433-437. doi: 10.12290/xhyxzz.2020-0091

Be on the Alert for Norovirus Epidemics and Outbreaks

doi: 10.12290/xhyxzz.2020-0091
Funds:

National Key Research and Development Program of China 2017YFC1601502

CAMS Innovation Fund for Medical Sciences 2016-I2M-1-014

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  • Corresponding author: CHEN Yu  Tel: 86-10-69159742, E-mail: c_yu@sina.com
  • Received Date: 2020-12-24
  • Accepted Date: 2020-12-28
  • Available Online: 2021-01-04
  • Publish Date: 2021-07-30
  • Norovirus is a linear single-stranded positive-sense RNA virus. It is one of the main pathogens causing acute gastroenteritis in humans. The transmission route of norovirus infection is complex, along with a low infection dose. Currently there are different laboratory-based detection methods, including direct microscopy, immunological assay, and molecular biology test. Being on the alert for norovirus epidemics and outbreaks, regulating patient management, hand hygiene, implementation of cleaning and disinfection measures, and health education are the key points of prevention and control of norovirus infection.
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  • [1] Bartsch SM, Lopman BA, Ozawa S, et al. Global Economic Burden of Norovirus Gastroenteritis[J]. PLoS One, 2016, 11: e0151219. doi:  10.1371/journal.pone.0151219
    [2] Shah MP, Hall AJ. Norovirus Illnesses in Children and Adolescents[J]. Infect Dis Clin North Am, 2018, 32: 103-118. doi:  10.1016/j.idc.2017.11.004
    [3] Zhou HL, Wang SM, von Seidlein L, et al. The epidemiology of norovirus gastroenteritis in China: disease burden and distribution of genotypes[J]. Front Med, 2020, 14: 1-7. doi:  10.1007/s11684-019-0733-5
    [4] Kapikian AZ. The discovery of the 27-nm Norwalk virus: an historic perspective[J]. J Infect Dis, 2000, 181: S295-S302. doi:  10.1086/315584
    [5] 周弘璐, 谭明, 汪萱怡. 诺如病毒的致病机制及诊断[J]. 微生物与感染, 2019, 14: 303-309. doi:  10.3969/j.issn.1673-6184.2019.05.007
    [6] Robilotti E, Deresinski S, Pinsky BA. Norovirus[J]. Clin Microbiol Rev, 2015, 28: 134-164. doi:  10.1128/CMR.00075-14
    [7] de Graaf M, van Beek J, Koopmans MP. Human norovirus transmission and evolution in a changing world[J]. Nat Rev Microbiol, 2016, 14: 421-433. doi:  10.1038/nrmicro.2016.48
    [8] 孙立梅, 李晖, 谭小华, 等. 2012—2014年广东省哨点医院诺如病毒GⅡ. 4 Sydney变异株流行状况及暴发疫情特征分析[J]. 中华预防医学杂志, 2015(7): 615-620. doi:  10.3760/cma.j.issn.0253-9624.2015.07.008
    [9] de Graaf M, Van Beek J, Vennema H, et al. Emerg-ence of a novel GⅡ. 17 norovirus-End of the GⅡ. 4 era?[J]. Euro Surveill, 2015, 20: 21178. http://europepmc.org/abstract/MED/26159308
    [10] Jin M, Zhou YK, Xie HP, et al. Characterization of the new GⅡ. 17 norovirus variant that emerged recently as the predominant strain in China[J]. J Gen Virol, 2016, 97: 2620-2632. doi:  10.1099/jgv.0.000582
    [11] 石鑫, 舒畅, 许军, 等. 黑龙江省2017—2019年腹泻患者诺如病毒检测及基因特征分析[J]. 中国公共卫生管理, 2020, 36: 457-459.
    [12] Teunis PF, Moe CL, Liu P, et al. Norwalk virus: how infectious is it?[J]. J Med Virol, 2008, 80: 1468-1476. doi:  10.1002/jmv.21237
    [13] Seitz SR, Leon JS, Schwab KJ, et al. Norovirus infectivity in humans and persistence in water[J]. Appl Environ Microbiol, 2011, 77: 6884-6888. doi:  10.1128/AEM.05806-11
    [14] Glass RI, Parashar UD, Estes MK. Norovirus gastroenteritis[J]. N Engl J Med, 2009, 361: 1776-1785. doi:  10.1056/NEJMra0804575
    [15] 中国疾病预防控制中心. 诺如病毒感染暴发调查和预防控制技术指南(2015版)[J]. 中国病毒病杂志, 2015, 5: 448-458.
    [16] Bitler EJ, Matthews JE, Dickey BW, et al. Norovirus outbreaks: a systematic review of commonly implicated transmission routes and vehicles[J]. Epidemiol Infect, 2013, 141: 1563-1571. doi:  10.1017/S095026881300006X
    [17] 董桂兰, 陈斯敏, 颜雪梅, 等. 某高校1起诺如病毒感染暴发调查[J]. 中国校医, 2018, 32: 441, 443.
    [18] Leshem E, Barclay L, Wikswo M, et al. Genotype GⅠ. 6 norovirus, United States, 2010-2012[J]. Emerg Infect Dis, 2013, 19: 1317-1320.
    [19] Leshem E, Wikswo M, Barclay L, et al. Effects and clinical significance of GⅡ. 4 Sydney norovirus, United States, 2012-2013[J]. Emerg Infect Dis, 2013, 19: 1231-1238. doi:  10.3201/eid1908.130458
    [20] 张萌, 龙遗芳, 郭莉敏, 等. 广东省2013—2017年3种基因型诺如病毒感染暴发疫情的流行特征[J]. 中华流行病学杂志, 2018, 39: 1210-1215. doi:  10.3760/cma.j.issn.0254-6450.2018.09.013
    [21] 周弘璐, 谭明, 汪萱怡. 诺如病毒的致病机制及诊断[J]. 微生物与感染, 2019, 14: 303-309. doi:  10.3969/j.issn.1673-6184.2019.05.007
    [22] 沈家瑜, 徐德顺, 韩建康. 诺如病毒检测技术研究应用进展[J]. 中国卫生检验杂志, 2014, 24: 1974-1976.
    [23] 方肇寅, 温乐英, 晋圣瑾, 等. 在我国腹泻患儿中发现诺瓦克样病霉感染[J]. 病毒学报, 1995: 215-219.
    [24] 何金林. 诺如病毒检验进展[J]. 中国卫生检验杂志, 2010, 20: 453-455.
    [25] Jiang X, Wang M, Graham DY, et al. Expression, self-assembly, and antigenicity of the Norwalk virus capsid protein[J]. J Virol, 1992, 66: 6527-6532. doi:  10.1128/jvi.66.11.6527-6532.1992
    [26] Vinjé J. Advances in laboratory methods for detection and typing of norovirus[J]. J Clin Microbiol, 2015, 53: 373-381. doi:  10.1128/JCM.01535-14
    [27] Aho-Laukkanen E, Hirvonen JJ, Saha K. Comparison of Xpert Norovirus and RidaGene Norovirus assays for the detection of noroviruses in clinical fecal specimens[J]. Eur J Clin Microbiol Infect Dis, 2017, 36: 1019-1022. doi:  10.1007/s10096-016-2884-5
    [28] Illingworth E, Taborn E, Fielding D, et al. Is closure of entire wards necessary to control norovirus outbreaks in hospital? Comparing the effectiveness of two infection control strategies[J]. J Hosp Infect, 2011, 79: 32-37. doi:  10.1016/j.jhin.2011.04.024
    [29] Maccannell T, Umscheid CA, Agarwal RK, et al. Guideline for the prevention and control of norovirus gastroenteritis outbreaks in healthcare settings[J]. Infect Control Hosp Epidemiol, 2011, 32: 939-969. doi:  10.1086/662025
    [30] Goldberg JL. Guideline Implementation: Hand Hygiene[J]. AORN J, 2017, 105: 203-212. doi:  10.1016/j.aorn.2016.12.010
    [31] Cheng VC, Wong LM, Tai JW, et al. Prevention of nosocomial transmission of norovirus by strategic infec-tion control measures[J]. Infect Control Hosp Epidemiol, 2011, 32: 229-237. doi:  10.1086/658330
    [32] 宋丹. 诺如病毒传播特征及防控措施研究进展[J]. 中国校医, 2020, 34: 633-636.
    [33] Nowak P, Topping JR, Fotheringham V, et al. Measurement of the virolysis of human GⅡ. 4 norovirus in response to disinfectants and sanitisers[J]. J Virol Methods, 2011, 174: 7-11. doi:  10.1016/j.jviromet.2011.03.004
    [34] Liu PB, Yuen Y, Hsiao HM, et al. Effectiveness of liquid soap and hand sanitizer against Norwalk virus on contaminated hands[J]. Appl Environ Microbiol, 2010, 76: 394-399. doi:  10.1128/AEM.01729-09
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