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Volume 12 Issue 2
May  2021
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ZHUANG Nan, LI Wen-bo, ZHU Qing-li. Value of Imaging in Diagnosis and Follow-up of Crohn's Disease Complicated with Intestinal Stricture[J]. Medical Journal of Peking Union Medical College Hospital, 2021, 12(2): 238-243. DOI: 10.12290/xhyxzz.20190117
Citation: ZHUANG Nan, LI Wen-bo, ZHU Qing-li. Value of Imaging in Diagnosis and Follow-up of Crohn's Disease Complicated with Intestinal Stricture[J]. Medical Journal of Peking Union Medical College Hospital, 2021, 12(2): 238-243. DOI: 10.12290/xhyxzz.20190117
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Value of Imaging in Diagnosis and Follow-up of Crohn's Disease Complicated with Intestinal Stricture

  • Department of Ultrasound, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

Funds: 

National Natural Science Foundation of China 81771855

CAMS Innovation Fund for Medical Sciences 2017-I2M-1-006

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  • Corresponding author:

    ZHU Qing-li   Tel: 86-10-69155493, E-mail: zqlpumch@126.com

  • Received Date: June 23, 2019
  • Accepted Date: October 29, 2019
  • Available Online: November 28, 2019
  • Issue Publish Date: May 29, 2021
    Graphical Abstract
    • Abstract
  • Intestinal stricture is one of the most common complications of Crohn's disease(CD). About 15% of CD patients can develop intestinal stricture within the first 10 years after diagnosis. CD complicated with intestinal stricture can be divided into inflammatory, fibrous and mixed types according to pathological changes. Patients with the inflammatory type can alleviate symptoms by drug treatment. In patients with the fibrous type, the affected intestinal segments can only be treated by interventional or surgical treatment. Therefore, it is very important for clinical decision-making to comprehensively evaluate the number, location and shape of narrow intestinal segments, and to distinguish the degree of inflammation and fibrosis of the intestinal wall. This article reviews the sensitivity and specificity of the main imaging methods including endoscopy, CT, MRI, and trans-abdominal ultrasound in the diagnosis of intestinal stricture. In recent years, many new imaging techniques have made great progress in differentiating inflammation and fibrosis of the narrow intestinal wall, which is expected to be widely used in clinical practice and to further improve the diagnosis and treatment of CD complicated with intestinal stricture.
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    • References (40)
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