Abstract: Breast cancer has become the most prevalent malignant tumor worldwide. Screening improves the rate of early detection and is important for the treatment and prognosis of breast cancer. Breast ultrasound is a common method for screening breast cancer, which can be used as a complementary screening tool to mammography to improve the rate of detection, or used for screening breast cancer alone. In recent years, the use of new techniques of ultrasound in screening breast cancer such as shear wave elastography and contrast-enhanced ultrasound, are rapidly developing. This article reviewed the research progress of clinical application of breast ultrasound in screening breast cancer.