维生素D与妊娠期糖尿病研究进展

Research Progress on Vitamin D and Gestational Diabetes Mellitus

  • 摘要: 妊娠期糖尿病是妊娠期最常见的并发症之一,是影响母婴健康的重要因素。孕期维生素D营养状态与葡萄糖代谢相关,提示维生素D可能参与了妊娠期糖尿病的发生/发展过程。维生素D缺乏在孕妇中普遍存在,目前关于维生素D与妊娠期糖尿病相关性、治疗和预防的研究结果仍然存在矛盾,未来需要设计高质量的多中心随机对照试验,以提高临床研究的解释力。

     

    Abstract: Gestational diabetes mellitus is one of the most common complications during pregnancy and an important factor affecting the health of mothers and babies. The level of vitamin D during pregnancy is related to glucose metabolism, which suggests that vitamin D may be involved in the occurrence and development of gestational diabetes mellitus. This review provides an overview of the correlation between vitamin D and gestational diabetes mellitus, as well as current status of vitamin D in the treatment and prevention for pregnant women in China. Vitamin D deficiency is common in pregnant women. The existing research on this topic is still controversial. High-quality randomized controlled trials with large samples are needed in the future to improve the explanation of clinical trials. The role of vitamin D in the treatment and prevention of gestational diabetes mellitus is worth anticipation.

     

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