Email Alert RSS
Volume 4 Issue 2
Apr.  2013
Turn off MathJax
Article Contents
Abstract
References
Related Articles
Di CHEN, Lue LI, Zhi-kun YANG, Fang-tian DONG. Spectral-domain Optical Coherence Tomography Findings of Choroidal Thickness in Eyes of Patients with Idiopathic Macular Holes[J]. Medical Journal of Peking Union Medical College Hospital, 2013, 4(2): 113-117. DOI: 10.3969/j.issn.1674-9081.2013.02.006
Citation: Di CHEN, Lue LI, Zhi-kun YANG, Fang-tian DONG. Spectral-domain Optical Coherence Tomography Findings of Choroidal Thickness in Eyes of Patients with Idiopathic Macular Holes[J]. Medical Journal of Peking Union Medical College Hospital, 2013, 4(2): 113-117. DOI: 10.3969/j.issn.1674-9081.2013.02.006
shu

Spectral-domain Optical Coherence Tomography Findings of Choroidal Thickness in Eyes of Patients with Idiopathic Macular Holes

  • Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

More Information
  • Corresponding author:

    DONG Fang-tian Tel: 010-69156351, E-mail:d_fangtian@163.com

  • Received Date: January 10, 2013
  • Issue Publish Date: April 29, 2013
    Graphical Abstract
    • Abstract
  •   Objective  To determine the choroidal thickness in the eyes with idiopathic macular hole (IMH) and the unaffected fellow eyes.
      Methods  Twenty IMH patients and 20 ageand sex-matched healthy controls were recruited. Enhanced depth images were obtained using spectal-domain optical coherence tomography. The choroidal thickness was measured in the subfoveal area and 1 mm and 2 mm away from the fovea in the nasal, temporal, superior and inferior regions.
      Results  The mean subfoveal area choroidal thickness was (161.53±50.50) μm in the eyes with IMH, (204.95±59.58) μm in the fellow eyes, and (248.00±63.40) μm in the control group (P=0.000). The choroidal thickness at all measured regions showed significant differences among three groups (P < 0.05). Compared with the control group, the choroidal thickness was significantly thinner in eyes with IMH (P < 0.01) and unaffected fellow eyes except for the superior choroidal thickness at 2 mm and inferior choroidal thickness at 2 mm (P < 0.05).
      Conclusion  Choroidal thickness decreases in eyes with IMH and may also reduce in the unaffected fellow eyes, suggesting that the development of IMH may be associated with the choroid perfusion.
    • FullText(HTML)
    • References (23)
  • [1]
    McCannel CA, Ensminger JL, Diehl NN, et al. Populationbased incidence of macular holes[J]. Ophthalmology, 2009, 116:1366-1369. DOI: 10.1016/j.ophtha.2009.01.052
    [2]
    McDonnell PJ, Fine SL, Hillis AI. Clinical features of idiopathic macular cysts and holes[J]. Am J Ophthalmol, 1982, 93:777-786. DOI: 10.1016/0002-9394(82)90474-3
    [3]
    Morgan CM, Schatz H. Involutional macular thinning:a premacularhole condition[J]. Ophthalmology, 1986, 93:153-161. http://www.sciencedirect.com/science/article/pii/S0161642086337679
    [4]
    Chung SE, Kang SW, Lee JH, et al. Choroidal thickness in polypoidal choroidal vasculopathy and exudative age-related macular degeneration[J]. Ophthalmology, 2011, 118:840-845. DOI: 10.1016/j.ophtha.2010.09.012
    [5]
    Imamura Y, Fujiwara T, Margolis R, et al. Enhanced depth imaging optical coherence tomography of the choroid in central serous chorioretinopathy[J]. Retina, 2009, 29:1469-1473. DOI: 10.1097/IAE.0b013e3181be0a83
    [6]
    Spaide RF, Koizumi H, Pozzoni MC. Enhanced depth imaging spectral-domain optical coherence tomography[J]. Am J Ophthalmol, 2008, 146:496-500. DOI: 10.1016/j.ajo.2008.05.032
    [7]
    Margolis R, Spaide RF. A pilot study of enhanced depth imaging optical coherence tomography of the choroid in normal eyes[J]. Am J Ophthalmol, 2009, 147:811-815. DOI: 10.1016/j.ajo.2008.12.008
    [8]
    Kim M, Kim SS, Kwon HJ, et al. Association between choroidal thickness and ocular perfusion pressure in young, healthy subjects:enhanced depth imaging optical coherence tomography study[J]. Invest Ophthalmol Vis Sci, 2012, 53:7710-7717. DOI: 10.1167/iovs.12-10464
    [9]
    Goldenberg D, Moisseiev E, Goldstein M, et al. Enhanced depth imaging optical coherence tomography:choroidal thickness and correlations with age, refractive error, and axial length[J]. Ophthalmic Surg Lasers Imaging, 2012, 43:296301. http://www.ncbi.nlm.nih.gov/pubmed/22589335
    [10]
    Fujiwara A, Shiragami C, Shirakata Y, et al. Enhanced depth imaging spectral-domain optical coherence tomography of subfoveal choroidal thickness in normal Japanese eyes[J]. Jpn J Ophthalmol, 2012, 56:230-235. DOI: 10.1007/s10384-012-0128-5
    [11]
    李略, 杨治坤, 董方田.应用增强深部成像的相干光断层扫描测量正常人脉络膜厚度[J].中华眼科杂志, 2012, 48:819-823. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=zhyk201209012
    [12]
    禹海, 夏国英, 高明宏.频域干涉光断层扫描观察正常人眼脉络膜厚度的研究[J].中华实用眼科杂志, 2012, 30:69-72. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=zgsyykzz201201017
    [13]
    Gass JD. Idiopathic senile macular hole:Its early stages and pathogenesis[J]. Arch Ophthalmol, 1988, 106:629-639. DOI: 10.1001/archopht.1988.01060130683026
    [14]
    Gass JD. Age-dependent idiopathic macular foramen. Current concepts of the pathogenesis, diagnosis, and treatment[J]. Ophthalmology, 1995, 92:617-625. http://europepmc.org/abstract/MED/8750985
    [15]
    Gordon LW, Glaser BM. Full thickness macular formation in eyes with a pre-existing complete posterior vitreous detachment[J]. Ophthalmology, 1995, 102:1702-1705. DOI: 10.1016/S0161-6420(95)30806-8
    [16]
    Targino A, Costa RA, Calucci D, et al. OCT findings in macular hole formation in eyes with complete vitreofoveal separation[J]. Ophthalmic Surg Lasers Imaging, 2008, 39:65-68. DOI: 10.3928/15428877-20080101-17
    [17]
    Aras C, Ocakoglu O, Akova N. Foveolar choroidal blood flow in idiopathic macular hole[J]. Int Ophthalmol, 2004, 25:225-231. DOI: 10.1007/s10792-005-5014-4
    [18]
    Reibaldi M, Boscia F, Avitabile T, et al. Enhanced depth imaging optical coherence tomography of the choroid in idiopathic macular hole:A cross-sectional prospective study[J]. Am J Ophthalmol, 2011, 151:112-117. DOI: 10.1016/j.ajo.2010.07.004
    [19]
    曾婧, 刘冉, 李加青, 等.特发性黄斑裂孔患者黄斑部脉络膜厚度分析[J].中华实用眼科杂志, 2012, 30:123-126.
    [20]
    Sharanjeet-Kaur, O'Donaghue E, Murray IJ. Spectral sensitivity in eyes with macular holes and their fellow eyes[J]. Clin Exp Optom, 2003, 86:385-389. DOI: 10.1111/j.1444-0938.2003.tb03083.x
    [21]
    Tuzson R, Varsanyi B, Nagy BV, et al. Role of multifocal electroretinography in the diagnosis of idiopathic macular hole[J]. Invest Ophthalmol Vis Sci, 2010, 51:1666-1670. DOI: 10.1167/iovs.09-4375
    [22]
    Ezra E, Wells JA, Gray RH, et al. Incidence of idiopathic fu ll-thickness macular holes in fellow eyes:A 5-year prospective natural history study[J]. Ophthalmology, 1998, 105:353-359. DOI: 10.1016/S0161-6420(98)93562-X
    [23]
    Ikuno Y, Kawaguchi K, Nouchi T, et al. Choroidal thickness in healthy Japanese subjects[J]. Invest Ophthalmol Vis Sci, 2010, 51:2173-2176. DOI: 10.1167/iovs.09-4383
    • Related Articles

  • Related Articles

    [2]Zhi-qiao ZHANG, Fang-tian DONG, Jun-jie YE, You-xin CHEN. Clinical Efficacy of Vitrectomy on Vitreomacular Traction Syndrome[J]. Medical Journal of Peking Union Medical College Hospital, 2014, 5(1): 100-103. DOI: 10.3969/j.issn.1674-9081.2014.01.021
    [3]Yu-mei JIN, Feng-rong AI, Yan LUO, Ying LI. Comparison of Central Corneal Thickness Before and After Mydriasis Measured with A-ultrasound Pachymetry and Pentacam Scheimpflug System[J]. Medical Journal of Peking Union Medical College Hospital, 2013, 4(4): 429-432. DOI: 10.3969/j.issn.1674-9081.2013.04.017
    [4]Zhi-kun YANG, Xuan ZOU, Fang-tian DONG. Free Internal Limiting Membrane Flap Transplantation for Unclosed Idiopathic Macular Holes[J]. Medical Journal of Peking Union Medical College Hospital, 2013, 4(4): 425-428. DOI: 10.3969/j.issn.1674-9081.2013.04.016
    [6]Hong DU, Rong-ping DAI, Fang-tian DONG. Spectral Domain Optical Coherence Tomography in Patients with Central Serous Chorioretinopathy[J]. Medical Journal of Peking Union Medical College Hospital, 2013, 4(2): 160-164. DOI: 10.3969/j.issn.1674-9081.2013.02.016
    [7]Nan MA, Jun-jie YE, You-xin CHEN, Ke TAN, Hui-ying ZHOU. Effectiveness of Vitrectomy for Polypoidal Choroidal Vasculopathy Associated with Vitreous Hemorrhage[J]. Medical Journal of Peking Union Medical College Hospital, 2013, 4(2): 145-149. DOI: 10.3969/j.issn.1674-9081.2013.02.013
    [8]Rong-ping DAI, Fang-tian DONG. Macular Morphological Changes of Persistent Subclinical Subretinal Fluid after Scleral Buckle Surgery:An Optical Coherence Tomography Study[J]. Medical Journal of Peking Union Medical College Hospital, 2013, 4(2): 141-144. DOI: 10.3969/j.issn.1674-9081.2013.02.012
    [9]Shuai TANG, Jie YI, Yu-guang HUANG. Cardiovascular Responses of Intubation with Shikani Seeing Optical Stylet and Macintosh Laryngoscope[J]. Medical Journal of Peking Union Medical College Hospital, 2012, 3(3): 314-317. DOI: 10.3969/j.issn.1674-9081.2012.03.015
    [10]Yu-mei JIN, Yue ZHANG, Hui LI, Bo-yue HU. Effects of Orthokeratology Lens on Corneal Endothelium and Corneal Thickness[J]. Medical Journal of Peking Union Medical College Hospital, 2011, 2(2): 155-158. DOI: 10.3969/j.issn.1674-9081.2011.02.014

Catalog

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (164) PDF downloads (5) Cited by()
    Related
    Links: National Health Commission of the People's Republic of China Chinese Academy of Medical Sciences(CAMS) AMLC Check CNKI Database CNKI Term Online Chinese General Practice
    Address：Room 302,Third Floor,Building 7, No. 1 Shuaifuyuan, Wangfujing, Dongcheng District, Beijing 100730, China
    Tel：010-69154261/4262
    E - mail：medj@pumch.cn mjpumch@126.com
    Copyright of website：Editorial Office of Medical Journal of Peking Union Medical College Hospital

    Supported by: Beijing Renhe Information Technology Co., Ltd.  Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return
    x Close Forever Close