Spectral Domain Optical Coherence Tomography in Patients with Central Serous Chorioretinopathy

  Objective  To study the clinical features of spectral domain optical coherence tomography (SD-OCT) scanning in patients with central serous chorioretinopathy (CSC).

  Methods  Thirty-four patients (40 eyes) with confirmed CSC underwent SD-OCT scanning and fundus fluorescein angiography (FFA). Clinical findings in both examinations were analyzed and compared.

  Results  As shown by SD-OCT, local neuro-retina detachments in macular areas were found in 37 of 40 eyes (92.5%), and retinal pigment epithelium (RPE) detachments without neuro-retina detachments were found in 3 eyes (7.5%). In the eyes with neoro-retina detachments, high and thickened signals of photoreceptor inner segment/outer segment (IS/OS) junction were found in 9 eyes (24.3%), and low or disappeared signals of IS/OS junction were found in 28 eyes (75.7%). Twenty of 37 eyes (54.1%) with neuro-retina detachments had RPE detachments, 12 eyes (32.4%) had small RPE elevations or thickened RPE layer. RPE detachments in both SD-OCT and FFA in 3 eyes kept consistent. In 28 eyes, RPE lesions in SD-OCT were found in the same area of the fluorescein leakage spots in FFA. More RPE detachments and neuro-retina detachments were found in SD-OCT than in FFA.

  Conclusions  Small RPE elevations, thickened RPE layer, or RPE detachments can be found in the retinal detachment areas by SD-OCT in most CSC patients. Low or disappeared signals may exist in the IS/OS junction.