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Volume 15 Issue 2
Mar.  2024
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CUI Quexuan, CHE Lu, XU Li. Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical Application[J]. Medical Journal of Peking Union Medical College Hospital, 2024, 15(2): 258-264. DOI: 10.12290/xhyxzz.2023-0552
Citation: CUI Quexuan, CHE Lu, XU Li. Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical Application[J]. Medical Journal of Peking Union Medical College Hospital, 2024, 15(2): 258-264. DOI: 10.12290/xhyxzz.2023-0552
shu

Baroreflex in Pain Regulation: Pathogenic Mechanism and Clinical Application

  • Department of Anesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

Funds: 

National High Level Hospital Clinical Research Funding 2022-PUMCH-B-119

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  • Corresponding author:

    XU Li, E-mail: pumchxuli@163.com

  • Received Date: November 19, 2023
  • Accepted Date: December 17, 2023
  • Available Online: December 21, 2023
  • Issue Publish Date: March 29, 2024
    Graphical Abstract
    • Abstract
  • The baroreceptor reflex is an essential mechanism for the autonomic nervous system in cardiovascular homeostasis and is closely related to pain regulation. Baroreflex sensitivity (BRS) is an indicator for quantitative evaluation of baroreflex reflex function. Pain sensitivity is negatively correlated with BRS, therefore, BRS has potential application prospects in pain risk prediction and therapeutic efficacy assessment. Vagus nerve stimulation, capable of activating the baroreceptor reflex, has been widely used in acute or chronic pain patients in recent years. This article reviews the mechanism and clinical application progress of the baroreceptor reflex in pain regulation, with the hope of providing reference for further exploring treatment to regulate baroreceptor reflex function in pain treatment.
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