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Volume 15 Issue 2
Mar.  2024
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LIU Miaomiao, YUE Hongmei, LI Yating, XU Jinhui, WU Xingdong, ZHU Haobin. Obstructive Sleep Apnea-induced Gut Dysbiosis and Ischaemic Stroke: Mechanism and Research Progress[J]. Medical Journal of Peking Union Medical College Hospital, 2024, 15(2): 382-386. DOI: 10.12290/xhyxzz.2023-0452
Citation: LIU Miaomiao, YUE Hongmei, LI Yating, XU Jinhui, WU Xingdong, ZHU Haobin. Obstructive Sleep Apnea-induced Gut Dysbiosis and Ischaemic Stroke: Mechanism and Research Progress[J]. Medical Journal of Peking Union Medical College Hospital, 2024, 15(2): 382-386. DOI: 10.12290/xhyxzz.2023-0452
shu

Obstructive Sleep Apnea-induced Gut Dysbiosis and Ischaemic Stroke: Mechanism and Research Progress

  • 1.

    The First Clinical Medical School, Lanzhou University, Lanzhou 730000, China

  • 2.

    Department of Pulmonary and Critical Care Medicine, the First Hospital of Lanzhou University, Lanzhou 730000, China

Funds: 

Science and Technology Project of Gansu Province 22ZD1FA00A

More Information
  • Corresponding author:

    YUE Hongmei, E-mail: yuehongmei18@sina.com

  • Received Date: September 24, 2023
  • Accepted Date: November 19, 2023
  • Available Online: November 21, 2023
  • Issue Publish Date: March 29, 2024
    Graphical Abstract
    • Abstract
  • Ischemic stroke, a cerebrovascular disease with high incidence, high mortality, high disability rate and high recurrence rate, is an important cause of death and disability of middle-aged and elderly people in China, and imposes a huge burden to society and families. Therefore, it is essential to identify the risk factors associated with ischemic stroke and effectively prevent them. Studies have shown that obstructive sleep apnea is an independent risk factor for ischemic stroke. However, the exact pathological mechanism of their association has not been clarified. With the development of next-generation sequencing technology, more and more studies have focused on intestinal microbiota. They have found that obstructive sleep apnea can cause intestinal microbiota changes, and intestinal microbiota may be closely related to ischemic stroke. Therefore, this paper attempts to investigate the relationship between intestinal flora and ischemic stroke, so as to reveal the potential pathological mechanism of ischemic stroke caused by obstructive sleep apnea.
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    • References (33)
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