Volume 14 Issue 4
Jul.  2023
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WANG Fang, CHEN Ying, LEI Huibin, ZHANG Huifeng, HE Jie, LI Meng, LEI Ting, ZHANG Wei. Clinical Application of Follicular Unit Extraction in Androgenetic Alopecia[J]. Medical Journal of Peking Union Medical College Hospital, 2023, 14(4): 808-813. doi: 10.12290/xhyxzz.2022-0716
Citation: WANG Fang, CHEN Ying, LEI Huibin, ZHANG Huifeng, HE Jie, LI Meng, LEI Ting, ZHANG Wei. Clinical Application of Follicular Unit Extraction in Androgenetic Alopecia[J]. Medical Journal of Peking Union Medical College Hospital, 2023, 14(4): 808-813. doi: 10.12290/xhyxzz.2022-0716

Clinical Application of Follicular Unit Extraction in Androgenetic Alopecia

doi: 10.12290/xhyxzz.2022-0716
Funds:

Natural Science Basic Research Program of Shaanxi Province in 2021 2021JQ-784

Shaanxi Science and Technology Program of Xi'an City in Shaanxi Province 21YXYJ0129

Shaanxi Science and Technology Office and Development 2022JM-528

University-level Scientific Research Innovation Team of Medical College in 2021 2021TD14

More Information
  • Corresponding author: ZHANG Wei, E-mail:doctorzhw@163.com
  • Received Date: 2022-12-15
  • Accepted Date: 2023-02-09
  • Publish Date: 2023-07-30
  •   Objective  To explore the clinical application of follicular unit extraction (FUE) hair transplantation in male androgen alopecia (AGA).  Methods  From August 2016 to September 2018, male AGA patients operated with FUE hair transplantation in the First Affiliated Hospital of Xi'an Medical University were retrospectively analyzed.At one year after transplantation, clinical curative effect was evaluated by the survival hair density and follicles rate of FUE transplantation, meanwhile surgical complications, patient satisfaction rate and life quality score were measured and analyzed.  Results  A total of 126 male AGA patients who met the inclusion and exclusion criteria were included, with average age was (37±9.05) years and average disease course was (10±2.76) years.According to the Hamilton-Norwood grade standard, there were 5 grade Ⅱpatients, 55 grade Ⅲ patients, 54 grade Ⅳ patients, 10 grade Ⅴ patients, and 2 grade Ⅵ patients.At one year after transplantation, viable hair density on the anterior hairline and the top of the head was (65±7) FUs/cm2 and (43±4) FUs/cm2, respectively.The survival rate of hair follicles was more than 90%, even more than 95% among the 107 AGA patients.The effective rate was 100%(126/126), no serious complications occurred, and the satisfaction rate of patients was 97.6%(123/126).Besides, the scores of physical function, psychological function, social function and material life status of 126 AGA patients were significantly increased than those before transplantation (all P < 0.01).  Conclusions  FUE hair transplantation has significant clinical effect, and is highly safe and effective.With the potential to dramatically improve life quality, it can be widely applied in treatment of AGA.
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  • [1] 中国医师协会美容与整形医师分会毛发整形美容专业委员会. 中国人雄激素性脱发诊疗指南[J]. 中国美容整形外科杂志, 2019, 30: 前插2-6. doi:  10.3969/j.issn.1673-7040.2019.01.001
    [2] Gupta AK, Venkataraman M, Talukder M, et al. Relative Efficacy of Minoxidil and the 5-α Reductase Inhibitors in Androgenetic Alopecia Treatment of Male Patients: A Network Meta-analysis[J]. JAMA Dermatol, 2022, 158: 266-274. doi:  10.1001/jamadermatol.2021.5743
    [3] Zhao Z, Tian Q, Zhang B. Effects of rehabilitation nursing care on deep vein thrombosis of the lower limbs following spinal fractures[J]. Am J Transl Res, 2021, 13: 1877-1883.
    [4] 尹梓贻, 曹国荣, 刘举利, 等. 瘢痕性秃发实施高密度毛发移植技术的治疗效果研究[J]. 中国医疗美容杂志, 2019, 9: 27-31. https://www.cnki.com.cn/Article/CJFDTOTAL-YLMR201905008.htm
    [5] Ghonemy S, Alarawi A, Bessar H. Efficacy and safety of a new 10% topical minoxidil versus 5% topical minoxidil and placebo in the treatment of male androgenetic alopecia: a trichoscopic evaluation[J]. J Dermatolog Treat, 2021, 32: 236-241. doi:  10.1080/09546634.2019.1654070
    [6] 张阳冰. 男性雄激素性脱发的BASP分型及疗效分析[D]. 广东. 广州医科大学, 2018.
    [7] 赵钧, 周圳滔, 张菊芳, 等. 毛发移植技术重建发际线的临床研究进展[J]. 组织工程与重建外科杂志, 2020, 16: 260-262. doi:  10.3969/j.issn.1673-0364.2020.03.022
    [8] Gan YY, Du LJ, Hong WJ, et al. Theoretical basis and clinical practice for FUE megasession hair transplantation in the treatment of large area androgenic alopecia[J]. J Cosmet Dermatol, 2021, 20: 210-217. doi:  10.1111/jocd.13432
    [9] Edoardo R, Giorgia C. Scalp Surgery: Quantitative Analysis of Follicular Unit Growth[J]. Plast Reconstr Surg Glob Open, 2015, 3: e539. doi:  10.1097/GOX.0000000000000524
    [10] Vasudevan B, Neema S, Ghosh K, et al. Hair transplanta-tion by follicular unit extraction for male androgenetic alopecia: A retrospective observational study from two centers[J]. Med J Armed Forces India, 2020, 76: 430-437. doi:  10.1016/j.mjafi.2019.11.001
    [11] Garg AK, Garg S. Donor harvesting: follicular unit excision[J]. J Cutan Aesthet Surg, 2018, 11: 195-201. doi:  10.4103/JCAS.JCAS_123_18
    [12] 张宝良, 施耘, 曹丽红, 等. 毛发移植发展现状[J]. 国际生物医学工程杂志, 2020, 43: 80-85. https://www.cnki.com.cn/Article/CJFDTOTAL-YLMR202007019.htm
    [13] Nadimi S. Complications with Hair Transplantation[J]. Facial Plast Surg Clin North Am, 2020, 28: 225-235. doi:  10.1016/j.fsc.2020.01.003
    [14] Chen HA, Pan JY, Chiang CH, et al. New idea for hair transplantation to preserve more donor hair follicles[J]. Med Hypotheses, 2019, 128: 83-85. doi:  10.1016/j.mehy.2019.05.018
    [15] 邱月棨, 付思祺, 罗帅寒天, 等. 2020年雄激素性脱发的研究进展[J]. 中华皮肤科杂志, 2021, 54: 835-838.
    [16] Umar S, Shitabata P, Rose P, et al. A New Universal Follicular Unit Excision Classification System for Hair Transplantation Difficulty and Patient Outcome[J]. Clin Cosmet Investig Dermatol, 2022, 15: 1133-1147. doi:  10.2147/CCID.S369346
    [17] Jimenez F, Alam M, Vogel JE, et al. Hair transplantation: Basic overview[J]. J Am Acad Dermatol, 2021, 85: 803-814. doi:  10.1016/j.jaad.2021.03.124
    [18] 苗勇, 朱德聪, 樊哲祥, 等. 移植胡须毛囊单位治疗男性雄激素性脱发[J]. 中华整形外科杂志, 2020, 36: 606-611. doi:  10.3760/cma.j.cn114453-20200407-00203
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