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Volume 14 Issue 2
Mar.  2023
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DONG Yaohua, SONG Hongmei. Neurological Manifestations in Familial Mediterranean Fever[J]. Medical Journal of Peking Union Medical College Hospital, 2023, 14(2): 334-338. DOI: 10.12290/xhyxzz.2022-0093
Citation: DONG Yaohua, SONG Hongmei. Neurological Manifestations in Familial Mediterranean Fever[J]. Medical Journal of Peking Union Medical College Hospital, 2023, 14(2): 334-338. DOI: 10.12290/xhyxzz.2022-0093
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Neurological Manifestations in Familial Mediterranean Fever

  • Department of Pediatrics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

Funds: 

National Key Research and Development Program of China 2021YFC2702001

Beijing Natural Science Foundation L202050

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  • Corresponding author:

    SONG Hongmei, E-mail: songhm1021@126.com

  • Received Date: February 28, 2022
  • Accepted Date: March 20, 2022
  • Available Online: October 05, 2022
  • Issue Publish Date: March 29, 2023
    Graphical Abstract
    • Abstract
  • Familial Mediterranean fever (FMF) is an autoinflammatory disease caused by mutations of the MEFV gene. The main clinical manifestations are recurrent fever and serous inflammation in various parts of the body. Some patients with FMF may also develop neurological manifestations such as epilepsy, demyelinating disease, aseptic meningitis. As neurological manifestations are rare in patients with FMF, the association between the two is often overlooked in clinical practice. In this paper, we reviewed the neurological manifestations of FMF and their relationship with genotypes, so as to deepen the understanding of the clinical manifestations of FMF and provide help for the diagnosis and treatment of patients with neurological manifestations.
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    • References (38)
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