Research Advances of Hyperlipidemic Pancreatitis

ZHAO Huijia; WU Dong; WU Wenming

doi:10.12290/xhyxzz.2021-0760

Volume 13 Issue 4

Jul. 2022

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Medical Journal of Peking Union Medical College Hospital > 2022 > 13(4): 637-643. > DOI: 10.12290/xhyxzz.2021-0760

ZHAO Huijia, WU Dong, WU Wenming. Research Advances of Hyperlipidemic Pancreatitis[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(4): 637-643. DOI: 10.12290/xhyxzz.2021-0760

Citation:

ZHAO Huijia, WU Dong, WU Wenming. Research Advances of Hyperlipidemic Pancreatitis[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(4): 637-643. DOI: 10.12290/xhyxzz.2021-0760

Citation:

ZHAO Huijia, WU Dong, WU Wenming. Research Advances of Hyperlipidemic Pancreatitis[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(4): 637-643. DOI: 10.12290/xhyxzz.2021-0760

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Research Advances of Hyperlipidemic Pancreatitis

ZHAO Huijia^{1, 3},
WU Dong^{2, 3},
WU Wenming^{1, 3, ,}

1.
Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
2.
Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
3.
State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

Funds:

National Key Research and Development Program of China 2019YFC1315901

Natural Science Foundation of Beijing Z190022

More Information

Corresponding author:
WU Wenming, E-mail: wuwm@pumch.cn
Received Date: November 28, 2021
Accepted Date: January 17, 2022
Available Online: March 04, 2022
Issue Publish Date: July 29, 2022

Graphical Abstract

Abstract

Abstract

Hyperlipidemic pancreatitis (HLP) is one of the most important causes of acute pancreatitis. The pathogenesis is associated with the accumulation of free fatty acids which can activate the inflammatory response. Compared with other causes, HLP is more likely to have the clinical features characterized by more severe symptoms, more complications, and higher likelihood of persistent organ failure. The HLP patients always need lipid lowering therapy such as apheresis or insulin therapy to reduce serum triglyceride rapidly. Assessment of the presence of hyperlipidemia in patients of acute pancreatitis and prompt management are crucial for the prognosis and the prevention of recurrence. This article reviews the etiology, pathogenesis, clinical features, and treatment of hypertriglyceridemia-induced acute pancreatitis.
- hyperlipidemic pancreatitis,
- hypertriglyceridemia,
- acute pancreatitis

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References (42)

References

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