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综合医院院级平台化样本库各类分库效能的比较

Comparisons of the Efficiency of Different Hospital-level Platform-based Sub-Biobanks in General Hospital

    摘要
  • 摘要:
      目的  提出综合医院平台化样本库各分库表现的评价方法, 并对各分库的综合表现进行评估, 以期为从事样本库建设的同仁提供参考。
      方法  将北京友谊医院2014年10月1日至2018年3月31日期间建立的所有样本分库纳入本研究。采用样本入库、样本应用以及样本质量3项指标进行分析评价, 并将上述3项指标赋予不同权重进行综合评估(样本入库30%、样本应用30%、样本质量40%)。
      结果  77个样本分库中, 项目库22个, 储备库55个。入库评分方面, 项目库和储备库差异无统计学意义(50.7±30.1比47.6±29.9, P=0.1614);应用评分、样本质量评分以及综合评分方面, 项目库均显著高于储备库应用评分:30.3(0, 84.2)比0(0, 31.6), P=0.0327;质量评分:100.0±0.0比94.5±22.9, P=0.0444;综合评分:62.5±14.8比57.9±17.9, P=0.0077。
      结论  综合医院院级平台化样本库中项目库的综合表现优于储备库。

     

    Abstract:
      Objective  The aim of this study was to present a method for evaluating the comprehensive performance of each platform-based sub-Biobanks of a general hospital in order to provide reasonable advice to new Biobankers.
      Methods  We conducted a comprehensive analysis of all these sub-Biobanks from three aspects including specimen incoming, specimen application, and specimen quality as well.We gave different weight of these 3 indicators for comprehensive evaluation(30% for incoming, 30% for application, and 40% for quality).
      Results  A total of 77 sub-Biobanks were included in this study, with 22 project-based Biobanks and 55 reserve Biobanks. There was no significant difference in specimen incoming scores between project-based banks and reserve banks (50.7±30.1 vs. 47.6±29.9, P=0.1614). Project-based Biobanks scored significantly better than reserve Biobanks in specimen application30.3(0, 84.2) vs. 0(0, 31.6), P=0.0327, specimen quality (100.0±0.0 vs. 94.5±22.9, P=0.0444), and comprehensive score (62.5±14.8 vs. 57.9±17.9, P=0.0077).
      Conclusion  Project-based Biobanks' comprehensive performance isbetter than that of reserve Biobanks in platform-based Biobanks of general hospitals.

     

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