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Advancements in the Application of ECMO in Pediatric Organ Transplantation
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摘要: 器官移植作为治疗儿童终末期器官功能衰竭的手段，随着手术技术、器官保存技术和免疫抑制药物的发展，手术成功率和受者长期生存质量不断得到提升。体外膜肺氧合（ExtracorporealMembrane Oxygenation,ECMO）在儿童器官移植受者中的应用，早期以心肺移植为主，逐渐拓展到对肝、肾等腹腔脏器移植围术期发生的心肺并发症的支持，以及用于供体的维护过程。随着ECMO技术和器械的不断升级，其在儿童终末期器官衰竭的支持治疗中地位越来越显著，让更多的器官功能衰竭儿童重获新生。Abstract: Organ transplantation, as a therapeutic option for children with end-stage organ failure, has seen continuous improvement in surgical techniques, organ preservation methods, and immunosuppressive drugs, leading to enhanced surgical success rates and long-term quality of life for recipients. Initially focused on heart and lung transplants in pediatric recipients, extracorporeal membrane oxygenation (ECMO) application has expanded to provide support for cardiopulmonary complications occurring during abdominal organ transplants such as liver and kidney, as well as for the maintenance of donor organs. With the ongoing advancements in ECMO technology and equipment, its significance in supporting therapy for end-stage organ failure in children is becoming increasingly prominent, granting a new lease on life to more children facing organ failure.
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Keywords:
- Organ transplantation /
- Pediatrics /
- ECMO /
- Perioperative support
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