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Advances in Etiology of High Incidence of Thyroid Cancer in Women
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摘要: 甲状腺癌是唯一以女性发病为主的非生殖性肿瘤，女性发病率为男性3倍，但现有研究尚未系统汇总分析女性甲状腺癌患病率高的原因，本文回顾女性甲状腺癌病因研究相关文献，总结女性甲状腺癌发病率高于男性的主要原因，包括雌激素、肥胖、生殖因素、氧化-抗氧化系统失衡、X染色体等，为未来甲状腺癌性别二态性研究提供方向，并为甲状腺癌性别差异性临床诊疗提供一定参考依据。Abstract: Thyroid cancer is the only non reproductive tumor that mainly occurs in women. The morbidity rate of female thyroid cancer is three times higher than that of male thyroid cancer. However, the existing studies have not systematically summarized the factors that contribute to the high incidence of thyroid cancer in women. This paper reviews all the literatures that mention the high incidence of thyroid cancer in women, and sorts out the main reasons, such as estrogen, obesity, reproductive factors, oxidation antioxidant system imbalance, X chromosome, etc., which are the main reasons for the current research finding that the incidence rate of thyroid cancer in women is higher than that in men. This paper makes a vivid graphic analysis and summary of the reasons, providing a research direction for future researchers to research on gender duality of thyroid cancer, and providing a certain reference for the clinical diagnosis and treatment of gender differences in thyroid cancer.
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Keywords:
- thyroid cancer /
- estrogen /
- obesity /
- X-chromosome /
- female /
- oxidation-antioxidant system
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