Abstract: Clinical practice guidelines represent the best recommendations for patient care, developed through a systematic review of the current available clinical evidence, and weighing the relative benefits and risks of various interventions. However, clinical practice guidelines need to go through a long translation cycle from development and revision to clinical promotion and application, and there are problems such as scattered distribution, high duplication rate, and low actual utilization. At present, the clinical practice guideline information platform can directly or indirectly solve the problems related to the lengthy revision cycles, decentralized dissemination and limited application of clinical practice guidelines. Therefore, this paper systematically examines different types of clinical practice guideline information platforms and investigates their corresponding challenges and emerging trends in platform design, data integration, and practical implementation, aiming to clarify the current status of this field and to provide a valuable reference for future research on clinical practice guideline information platforms.