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老年脓毒症患者围术期管理专家共识(2021年)

Expert Consensus on Perioperative Management of Elderly Septic Patients (2021)

    摘要
  • 摘要: 随着人口老龄化加剧，老年患者手术量呈指数上升。一些危险因素如共病、用药前状态、营养不良、虚弱和免疫系统功能受损等与老年患者脓毒症的高易感性相关，这些因素不仅增加了脓毒症的发生风险，还可导致更严重的感染，并可能与更高的死亡率相关。与非老年患者相比，老年脓毒症患者的预后更差，但其治疗并无显著差异。此外，老年脓毒症幸存者的生活质量也较差。因此，为优化老年脓毒症患者围术期管理，相关学科临床专家就该问题进行讨论并制订了此共识。

     

    Abstract: As the increasing of the aging population, the number of elderly surgical patients has increased exponentially.In elderly patients, a number of risk factors, such as comorbidities, premedication status, malnutrition, weakness, and impaired function of the immune system (or immune senescence), which are associated with a higher susceptibility to sepsis.These factors not only increase the risk of sepsis, but also lead to more severe manifestations of infection and may be associated with higher mortality.Elderly patients with sepsis had a poor prognosis compared to non-elderly patients, but there was no significant difference in the treatment.In addition, the survivors of elderly septic patients also had poorer quality of life.Therefore, in order to optimize the perioperative management of elderly patients, clinical experts from relevant disciplines discussed this issue and formulated this consensus.

     

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