Abstract: In recent years, with the improvement of people's quality of life and the deepening of the understanding of the disease, opportunistic hysterectomy or adnexal resection has become a hot issue of concern to clinicians and patients. In this paper, based on the analysis of the advantages and disadvantages of hysterectomy, it is pointed out that hysterectomy can reduce the risk of cervical cancer or endometrial cancer in the high-risk group, but it may have negative effects on pelvic floor function, sexual satisfaction, and psychology. Whether selecting hysterectomy should be performed at the same time of the salpingo-oophorectomy for postmenopausal patients, several factors should be considered at the same time, including: the risk of cervical cancer and endometrial cancer, the patient's physical condition, and the experience of the surgeon. Opportunistic salpingectomy should be considered for women scheduled for hysterectomy due to benign disease in order to reduce the incidence of epithelial ovarian cancer. However, bilateral salpingo-oophorectomy should be performed in patients diagnosed with breast cancer if hysterectomy is planned in order to reduce the mortality of breast cancer.