Volume 1 Issue 1
Jul.  2010
Turn off MathJax
Article Contents
Han-zhong LI, Jin WEN, Zhi-gang JI, He XIAO, Wei-gang YAN, Wei-feng XU, Zheng-pei ZENG, Yu-guang HUANG, Da-wei LIU. Laparoscopic Surgery for Adrenal Pheochromocytoma and Paraganglioma:Report of 211 Cases[J]. Medical Journal of Peking Union Medical College Hospital, 2010, 1(1): 72-76.
Citation: Han-zhong LI, Jin WEN, Zhi-gang JI, He XIAO, Wei-gang YAN, Wei-feng XU, Zheng-pei ZENG, Yu-guang HUANG, Da-wei LIU. Laparoscopic Surgery for Adrenal Pheochromocytoma and Paraganglioma:Report of 211 Cases[J]. Medical Journal of Peking Union Medical College Hospital, 2010, 1(1): 72-76.

Laparoscopic Surgery for Adrenal Pheochromocytoma and Paraganglioma:Report of 211 Cases

More Information
  • Corresponding author: LI Han-zhong Tel; 010-65296035, E-mail:lihanzhong@medmails.com.cn
  • Received Date: 2010-03-24
  • Publish Date: 2010-07-30
  •   Objective  To explore the effectiveness and safety of laparoscopic surgery in treating adrenal pheochromocytomas and paragangliomas.  Methods  The clinical data of 211 patients with pathologically confirmed adrenal pheochromocytomas (n=170) or paragangliomas (n=41) (ranges 2-16 cm in diameter) treated with laparoscopic surgery in our center from 2003 to 2010 were retrospectively reviewed. Endocrine examinations, ultrasound, CT, MRI, and 131I MIBG were performed before surgery. Patients also received α-receptor blocker for 2-4 weeks preoperatively.  Results  All the operations were successfully performed, with a mean operating time of (97±29) min (60-170 min) and a mean estimated blood loss of (84.6±56.3) ml (15-250 ml). The mean hospital stay after operation was (4.9±1.6) days (3-7 days). No major intraoperative complication was noted. Patients were followed up for 3-84 months, and 12 experienced recurrences, which were further diagnosed as malignant tumors.  Conclusions  Surgery is required once a diagnosis of adrenal pheochromocytoma or paraganglioma is confirmed. Laparoscopic surgery is a safe and minimally invasive procedure for adrenal pheochromocytomas and paragangliomas.
  • loading
  • [1] Parnaby CN, Serpell MG, Connell JM, et al. Perioperative haemodynamic changes in patients undergoing laparoscopie adrenalectomy for phaeochromocytomas and other adrenal tumours[J]. Surgeon, 2010, 8: 9-14. doi:  10.1016/j.surge.2009.10.009
    [2] Yamaguchi T, Tada M, Takashi H, et al. An incidentally discovered small and asymptomatic para-aortic paraganglioma[J]. Eur Surg Res, 2008, 40:14-18. doi:  10.1159/000107616
    [3] Chidirm G, Rojnoveanu G, Mishin I, et al. Extra-adrenal nonfunetional retroperitoneal paraganglioma: case report and review of the literature[J]. Int Surg, 2005, 90: 275-278. https://pubmed.ncbi.nlm.nih.gov/16625946/
    [4] Matsui H, Ikeuchi s, Onoda N, et al. Malignant paraganglioma of the retroperitoneum with lung metastases: a 13year survivor after radical surgery[J]. Asian J Surg, 2007, 30: 75-79. doi:  10.1016/S1015-9584(09)60133-0
    [5] Shi BB, Li HZ, Chen C, et al. Differential diagnosis and laparoscopic treatment of adrenal pheochromocytoma and ganglioneuroma[J]. Chin Med J (Engl), 2009, 5:17901793. http://cn.bing.com/academic/profile?id=45e0742168694c7b3c984ab427bbdde9&encoded=0&v=paper_preview&mkt=zh-cn
    [6] 李汉忠, 臧美孚, 徐大.腹腔镜肾上腺肿瘤切除[J].中华外科杂志, 1994, 6:345-347. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=QK199400610265
    [7] 李汉忠, 严维刚, 王伟.肾上腺意外瘤126例分析[J].中华外科杂志, 2004, 2:97-99. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=zhwk200402011
    [8] Gagner M, Lacroix A, Bolte E. Laparoscopic adrenalectomy in Cushings syndrome and pheochromocytoma[J]. N Engl J Med, 1992, 327:1033. doi:  10.1056/NEJM199210013271417
    [9] Rocha FM, Faramarzi-Roques R, Tauzin-FinP, et al. Laparoscopic surgery for pheochromocytoma[J]. Eur Urol, 2004, 45: 226-232. doi:  10.1016/j.eururo.2003.09.016
    [10] Berber E, Tllioglu G, Harvey A. Comparison of laparoscopic transabdominal lateral versus posterior retroperitoneal. adrenalectomy[J]. Surgery, 2009, 146: 621-625. doi:  10.1016/j.surg.2009.06.057
    [11] Eisenhofer G, Bornstein SR, Brouwers FM, et al. Malignant pheochromocytoma: current status and initiatives for future progress[J]. Endocr Relat Cancer, 2004, 11: 423-436. http://cn.bing.com/academic/profile?id=b2f7b17dc3afc27547c5922423ede050&encoded=0&v=paper_preview&mkt=zh-cn
    [12] Hwang J, Shoaf G, Uchio EM, et al. Laparoscopic management of extra-adrenal pheochromocytoma[J]. J Urol, 2004, 171: 72-76. http://cn.bing.com/academic/profile?id=d9bef64d95de4c4d7c88bd7b9324d457&encoded=0&v=paper_preview&mkt=zh-cn
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(2)

    Article Metrics

    Article views (199) PDF downloads(8) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return