Neuroendocrine Neoplasias Related to Hypertension: Current Status and Progress

Neuroendocrine neoplasias (NENs) are rare. Some NENs secrete hormone, thus causing hypertension of the patients. NENs are important causes of secondary hypertension, which include pheochromocytoma and paraganglioma, growth hormone-secreting pituitary adenoma, adrenocorticotropic hormone-secreting pituitary adenoma, parathyroid adenoma and carcinoma, and ectopic hormone-secreting NENs. Apart from hypertension, most NEN patients had other typical clinical features that need to be identified at early stage. In recent years, with the application of new technologies of nuclide imaging, the detection rate of these diseases has been greatly improved, and more patients can be diagnosed and treated early.