Shi-Yang JIANG, Ping PENG, Xin-Yan LIU. Successful Labor Induction and Vaginal Delivery of Twin Pregnancy with Hydatidiform Mole and a Coexistent Fetus at 16 Weeks of Gestation: A Case Report[J]. Medical Journal of Peking Union Medical College Hospital, 2020, 11(3): 309-313. DOI: 10.3969/j.issn.1674-9081.20170229
Citation: Shi-Yang JIANG, Ping PENG, Xin-Yan LIU. Successful Labor Induction and Vaginal Delivery of Twin Pregnancy with Hydatidiform Mole and a Coexistent Fetus at 16 Weeks of Gestation: A Case Report[J]. Medical Journal of Peking Union Medical College Hospital, 2020, 11(3): 309-313. DOI: 10.3969/j.issn.1674-9081.20170229

Successful Labor Induction and Vaginal Delivery of Twin Pregnancy with Hydatidiform Mole and a Coexistent Fetus at 16 Weeks of Gestation: A Case Report

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  • Corresponding author:

    PENG Ping Tel: 86-10-69156208, E-mail: pengping2164@sina.com

  • Received Date: October 31, 2017
  • Issue Publish Date: May 29, 2020
  • Hydatidiform mole is a benign gestational trophoblastic disease. Twin pregnancy with hydatidi-form mole and a coexistent fetus is extremely rare. The diagnosis is usually delayed and the pregnancy is often terminated due to severe vaginal bleeding or other complications. There are few guidelines for termination methods. Here we report a case of successful labor induction and vaginal delivery of twin pregnancy with hydatidiform mole and a coexistent fetus at 16 weeks of gestation. The diagnosis, treatment principles, and termination methods are discussed.
  • [1]
    Sebire NJ, Foskett M, Paradinas FJ, et al. Outcome of twin pregnancies with complete hydatidiform mole and healthy co-twin[J]. Lancet, 2002,359:2165-2166. DOI: 10.1016/S0140-6736(02)09085-2
    [2]
    Niemann I, Sunde L, Peterson LK. Evaluation of the risk of persistent trophoblastic disease after twin pregnancy with diploid hydatidiform mole and coexisting normal fetus[J]. Am J Obstet Gynecol, 2007,197:451-455. DOI: 10.1016/j.ajog.2007.02.038
    [3]
    Lin LH, Maestá I, Braga A, et al. Multiple pregnancies with complete mole and coexisting normal fetus in North and South America:a retrospective multicenter cohort and literature review[J]. Gynecol Oncol, 2017,145:88-95. https://www.sciencedirect.com/science/article/pii/S0090825817300653
    [4]
    Kutuk MS, Ozgun MT, Dolanbay M, et al. Sonographic findings and perinatal outcome of multiple pregnancies associating a complete hydatidiform mole and a live fetus:a case series[J]. J Clin Ultrasound, 2014,42:465-471. DOI: 10.1002/jcu.22169
    [5]
    张爱青, 魏瑗, 张春妤, 等. 双胎之一完全性葡萄胎产前超声特征与临床结局对照分析[J]. 中华医学超声杂志(电子版), 2016,08:603-608. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=zhyxcszz201608010
    [6]
    Himoto Y, Kido A, Minamiguchi S, et al. Prenatal differential diagnosis of complete hydatidiform mole with a twin live fetus and placental mesenchymal dysplasia by magnetic resonance imaging[J]. J Obstet Gynaecol Res, 2014,40:1894-1900. DOI: 10.1111/jog.12441
    [7]
    戚庆炜, 向阳, 郝娜, 等. 双胎之一完全性葡萄胎的产前诊断及处理[J]. 中华妇产科杂志, 2003,10:6-9. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=zhfck200310002
    [8]
    Uemura N, Takai Y, Mikami Y, et al. Molecular cyto-genetic analysis of a hydatidiform mole with coexistent fetus:a case report[J]. J Med Case Rep, 2019,13:256. DOI: 10.1186/s13256-019-2180-y
    [9]
    Nobuhara I, Harada N, Haruta N, et al. Multiple metastatic gestational trophoblastic disease after a twin pregnancy with complete hydatidiform mole and coexisting fetus, following assisted reproductive technology:case report and literature review[J]. Taiwan J Obstet Gynecol, 2018,57:588-593. DOI: 10.1016/j.tjog.2018.06.020
    [10]
    祝洪澜,李艺,刘国莉,等. 34例双胎妊娠完全性葡萄胎与正常胎儿共存临床特征的荟萃分析[J]. 中国妇产科临床杂志, 2015,06:523-527. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=zgfcklczz201506013
    [11]
    Klatt TE, Franciosi RA, Cruikshank DP. Normal fetus with a twin presenting as both a complete hydatidiform mole and placenta previa[J]. Obstet Gynecol, 2006,107:527-530. DOI: 10.1097/00006250-200602001-00037
    [12]
    Kim CH, Kim YH, Kim JW, et al. Triplet pregnancy with partial hydatidiform mole coexisting with two fetuses:A case report[J]. J Obstet Gynaecol Res,2008,34:641-644. DOI: 10.1111/j.1447-0756.2008.00899.x
    [13]
    Zhou X, Chen Y, Li Y, Duan Z. Partial hydatidiform mole progression into invasive mole with lung metastasis following in vitro fertilization[J]. Oncol Lett, 2012,3:659-661. DOI: 10.3892/ol.2011.542
    [14]
    Wang Y, Qian H, Wang J. Medical termination of a partial hydatidiform mole and coexisting fetus during the second trimester:A case report[J]. Oncol Lett,2015,10:3625-3628. DOI: 10.3892/ol.2015.3743
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