Volume 4 Issue 2
Apr.  2013
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Jing XU, Yang JIANG, Ying LI, Zhong-hai WANG, Yu-mei JIN, Wen-wei XIA. Comparison of Laser in situ Keratomileusis Flap Made by Femtosecond Laser and Mechanical Microkeratome[J]. Medical Journal of Peking Union Medical College Hospital, 2013, 4(2): 123-127. doi: 10.3969/j.issn.1674-9081.2013.02.008
Citation: Jing XU, Yang JIANG, Ying LI, Zhong-hai WANG, Yu-mei JIN, Wen-wei XIA. Comparison of Laser in situ Keratomileusis Flap Made by Femtosecond Laser and Mechanical Microkeratome[J]. Medical Journal of Peking Union Medical College Hospital, 2013, 4(2): 123-127. doi: 10.3969/j.issn.1674-9081.2013.02.008

Comparison of Laser in situ Keratomileusis Flap Made by Femtosecond Laser and Mechanical Microkeratome

doi: 10.3969/j.issn.1674-9081.2013.02.008
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  • Corresponding author: LI Ying Tel: 010-69151668, E-mal:liyingpumch@sohu.com
  • Received Date: 2013-01-30
  • Publish Date: 2013-04-30
  •   Objective  To compare the effect of laser in situ keratomileusis (LASIK) surgery after flap creation with a femtosecond laser and a mechanical microkeratome.  Methods  Totally 300 eyes of 150 cases after FEMTO LDV femtosecond laser LASIK surgery (F-LASIK group) and 300 eyes of 150 cases after mechanical microkeratome LASIK surgery (M-LASIK group) were included from our department from July 2011 to July 2012. Uncorrcted visual acuity, dry-eye syndromes including tear film break-up time (BUT), Schirmer Ⅰ test, and corneal fluorescein staining, corneal topography data, and subjective symptoms evaluated with questionnaire were recorded and compared between these two groups.  Results  Primary healing was achieved in both groups. In F-LASIK group, 1 eye had a little fold of flap on the fist postoperative day, which was improved after washing. The expected uncorrected visual acuity was achieved within 1 month after surgery in both groups. The values of steep keratometric power (K1) and flat keratometric power (K2) were significantly decreased 1 month after operation in both groups (P < 0.05), whereas no significant difference was found between these two groups (P>0.05). BUT and Schirmer Ⅰ test results were significantly declined 1 month after surgery, and the FS score significantly increased (P < 0.05). One month after the operation, the average BUT was significantly longer in F-LASIK group than in M-LASIK group (P=0.045). Schirmer Ⅰ test results and the FS score were not significantly different between these two groups (P>0.05). The total score of 9 symptoms in F-LASIK group was significantly lower than that in M-LASIK group (Z=-0.989, P=0.043). The score of satisfaction in F-LASIK group was significantly higher than that in M-LASIK group (Z=-2.316, P=0.021).  Conclusions  Both traditional LASIK and FEMTO LDV LASIK can achieve good visual acuity and improve quality of life. However, the incidence and severity of dry eye is lower in FEMTO LDV LASIK than in traditional LASIK.
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  • [1] Issa A, Al HU. Femtosecond laser flap parameters and visual outcomes in laser in situ keratomileusis[J]. J Cataract Refr act Surg, 2011, 37:665-674. doi:  10.1016/j.jcrs.2010.10.049
    [2] Vryghem JC, Devogelaere T, Stodulka P. Efficacy, safety, and flap dimensions of a new femtosecond laser for laser in situ keratomileusis[J]. J Cataract Refract Surg, 2010, 36:442-448. doi:  10.1016/j.jcrs.2009.09.030
    [3] 陈跃国.应重视准分子激光角膜屈光手术对角膜生物力学结构完整性的影响[J].中华眼科杂志, 2011, 47:577-579. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=zhyk201107001
    [4] Wilson SE. Laser in situ keratomileusis-induced (presumed) neurotrophic epitheliopathy[J]. Ophthalmology, 2001, 108:1082-1087. doi:  10.1016/S0161-6420(01)00587-5
    [5] Battat L, Macri A, Dursun D, et al. Effects of laser in situ keratomileusis on tear production, clearance, and the ocular surface[J]. Ophthalmology, 2001, 108:1230-1235. doi:  10.1016/S0161-6420(01)00623-6
    [6] Korn BS, Kikkawa DO, Schanzlin DJ. Blepharoplasty in the post-laser in situ keratomileusis patient:preoperative considerations to avoid dry eye syndrome[J]. Plast Reconstr Surg, 2007, 119:2232-2239. doi:  10.1097/01.prs.0000260750.15059.17
    [7] Golas L, Manche EE. Dry eye after laser in situ keratomileusis with femtosecond laser and mechanical keratome[J]. J Cataract Refract Surg, 2011, 37:1476-1480. doi:  10.1016/j.jcrs.2011.03.035
    [8] Albietz JM, Lenton LM, Mclennan SG. Effect of laser in situ keratomileusis for hyperopia on tear film and ocular surface[J]. J Refract Surg, 2002, 18:113-123. doi:  10.3928/1081-597X-20020301-02
    [9] Kumano Y, Matsui H, Zushi I, et al. Recovery of corneal sensation after myopic correction by laser in situ keratomileusis with a nasal or superior hinge[J]. J Cataract Refract Surg, 2003, 29:757-761. doi:  10.1016/S0886-3350(02)01840-0
    [10] Zhang F, Deng S, Guo N, et al. Confocal comparison of corneal nerve regeneration and keratocyte reaction between FSLASIK, OUP-SBK, and conventional LASIK[J]. Invest Ophthalmol Vis Sci, 2012, 53:5536-5544. doi:  10.1167/iovs.11-8786
    [11] 买志彬, 张金嵩, 刘苏冰, 等. FEMTO LDV飞秒激光制瓣LASIK术后像差的改变[J].眼科新进展, 2010, 30:869-871, 875. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=ykxjz201009019t
    [12] Pallikaris IG, Kymionis GD, Panagopoulou SI, et al. Induced optical aberrations following formation of a laser in situ keratomileusis flap[J]. J Cataract Refract Surg, 2002, 28:17371741. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=7973db5930a7f284d7b76bb2a9742879
    [13] Tran DB, Sarayba MA, Bor Z, et al. Randomized prospective clinical study comparing induced aberrations with IntraLase and Hansatome flap creation in fellow eyes:potential impact on wavefront-guided laser in situ keratomileusis[J]. J Cataract Refract Surg, 2005, 31:97-105. doi:  10.1016/j.jcrs.2004.10.037
    [14] Durrie DS, Kezirian GM. Femtosecond laser versus mechanical keratome flaps in wavefront-guided laser in situ keratomileusis:prospective contralateral eye study[J]. J Cataract Refract Surg, 2005, 31:120-126. doi:  10.1016/j.jcrs.2004.09.046
    [15] Buzzonetti L, Petrocelli G, Valente P, et al. Comparison of corneal aberration changes after laser in situ keratomileusis performed with mechanical microkeratome and IntraLase femtosecond laser:1-year follow-up[J]. Cornea, 2008, 27:174-179. doi:  10.1097/ICO.0b013e31815a50bf
    [16] Ambrosio RJ, Tervo T, Wilson SE. LASIK-associated dry eye and neurotrophic epitheliopathy:pathophysiology and strategies for prevention and treatment[J]. J Refract Surg, 2008, 24:396-407. doi:  10.3928/1081597X-20080401-14
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