| Citation: |
CHEN Yuan, XU Qiang, WANG Weibin, ZHANG Taiping, GUO Junchao. Multidisciplinary Treatment of Pancreatic Cancer: Development and Experience of PUMCH[J]. Medical Journal of Peking Union Medical College Hospital, 2024, 15(4): 758-763. DOI: 10.12290/xhyxzz.2024-0281
|
Pancreatic cancer is a common malignant tumor in the digestive tract, and the difficulty of early diagnosis and the lack of effective treatment means are the main reasons for the poor prognosis of pancreatic cancer. In recent years, multidisciplinary treatment (MDT) has become an important means to break through the bottleneck of diagnosis and treatment of pancreatic cancer and improve clinical prognosis. Besides providing patients with high-quality diagnosis and treatment services, this treatment model helps to improve the clinical diagnosis and treatment level of specialists and cultivate high-quality compound medical talents. It also highlights clinical research groups and high-quality case resource sharing, and promotes the clinical application of innovative drugs and new diagnostic and therapeutic technologies, which plays an essential role in increasing the core competence of hospitals. This paper reviews and summarizes the origin, status quo, and deficiencies of the MDT diagnosis and treatment model of pancreatic cancer in China, and examines the prospects for future development, with the aim to provide reference for domestic and foreign counterparts.
| [1] |
Siegel R L, Giaquinto A N, Jemal A. Cancer statistics, 2024[J]. CA Cancer J Clin, 2024, 74(1): 12-49. DOI: 10.3322/caac.21820
|
| [2] |
Bray F, Laversanne M, Sung H, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2024, 74(3): 229-263. DOI: 10.3322/caac.21834
|
| [3] |
Christenson E S, Jaffee E, Azad N S. Current and emerging therapies for patients with advanced pancreatic ductal adenocarcinoma: a bright future[J]. Lancet Oncol, 2020, 21(3): e135-e145. DOI: 10.1016/S1470-2045(19)30795-8
|
| [4] |
Wood L D, Canto M I, Jaffee E M, et al. Pancreatic cancer: pathogenesis, screening, diagnosis, and treatment[J]. Gastroenterology, 2022, 163(2): 386-402.e1. DOI: 10.1053/j.gastro.2022.03.056
|
| [5] |
Ullman N A, Burchard P R, Dunne R F, et al. Immuno-logic strategies in pancreatic cancer: making cold tumors hot[J]. J Clin Oncol, 2022, 40(24): 2789-2805. DOI: 10.1200/JCO.21.02616
|
| [6] |
中国医师协会肿瘤医师分会, 中国医疗保健国际交流促进会胰腺疾病专家委员会, 中国医药教育协会腹部肿瘤专家委员会. 中国胰腺癌多学科综合治疗模式专家共识(2020版)[J]. 临床肝胆病杂志, 2020, 36(9): 1947-1951. DOI: 10.3969/j.issn.1001-5256.2020.09.007
Chinese Society for Clinical Oncologists, Expert Committee on Pancreatic Diseases, China International Exchange and Promotive Association for Medical and Health Care, Expert Committee on Abdominal Neoplasms, China Medicine Education Association. Expert consensus on the MDT model of pancreatic cancer in China (2020 version)[J]. J Clin Hepatol, 2020, 36(9): 1947-1951. DOI: 10.3969/j.issn.1001-5256.2020.09.007
|
| [7] |
Pillay B, Wootten A C, Crowe H, et al. The impact of multidisciplinary team meetings on patient assessment, management and outcomes in oncology settings: a systematic review of the literature[J]. Cancer Treat Rev, 2016, 42: 56-72. DOI: 10.1016/j.ctrv.2015.11.007
|
| [8] |
Lowes M, Kleiss M, Lueck R, et al. The utilization of multidisciplinary tumor boards (MDT) in clinical routine: results of a health care research study focusing on patients with metastasized colorectal cancer[J]. Int J Colorectal Dis, 2017, 32(10): 1463-1469. DOI: 10.1007/s00384-017-2871-z
|
| [9] |
高扬, 邵雨辰, 苏明珠, 等. 癌症患者的多学科团队协作诊疗模式研究进展[J]. 中国医院管理, 2019, 39(3): 34-37. https://www.cnki.com.cn/Article/CJFDTOTAL-YYGL201903016.htm
Gao Y, Shao Y C, Su M Z, et al. Advances in the research of multidisciplinary team cooperative diagnosis and treatment model for cancer patients[J]. Chin Hosp Manag, 2019, 39(3): 34-37. https://www.cnki.com.cn/Article/CJFDTOTAL-YYGL201903016.htm
|
| [10] |
Tempero M A, Malafa M P, Al-Hawary M, et al. Pancreatic adenocarcinoma, version 2.2021, NCCN clinical practice guidelines in oncology[J]. J Natl Compr Canc Netw, 2021, 19(4): 439-457. DOI: 10.6004/jnccn.2021.0017
|
| [11] |
Conroy T, Pfeiffer P, Vilgrain V, et al. Pancreatic cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up[J]. Ann Oncol, 2023, 34(11): 987-1002. DOI: 10.1016/j.annonc.2023.08.009
|
| [12] |
创新疑难病诊疗模式 树立多学科协作典范 北京协和医院胰腺疾病会诊中式开诊百次记实[J]. 协和医学杂志, 2012, 3(4): 358.
Innovative diagnosis and treatment model for difficult diseases, establishing a model of multidisciplinary collaboration, and Peking Union Medical College Hospital's pancreatic disease consultation with Chinese style: a record of 100 Chinese style consultations[J]. Med J PUMCH, 2012, 3(4): 358.
|
| [13] |
Gardner T B, Barth R J, Zaki B I, et al. Effect of initiating a multidisciplinary care clinic on access and time to treatment in patients with pancreatic adenocarcinoma[J]. J Oncol Pract, 2010, 6(6): 288-292. DOI: 10.1200/JOP.2010.000041
|
| [14] |
Hansen M F C, Storkholm J H, Hansen C P. The results of pancreatic operations after the implementation of multidisciplinary team conference (MDT): a quality improvement study[J]. Int J Surg, 2020, 77: 105-110.
|
| [15] |
Guo J C, Zhang P, Zhou L, et al. Prognostic and predictive value of a five-molecule panel in resected pancreatic ductal adenocarcinoma: a multicentre study[J]. EBioMedicine, 2020, 55: 102767. DOI: 10.1016/j.ebiom.2020.102767
|
| [16] |
Dai M H, Liu Q F, Xing C, et al. Early drain removal is safe in patients with low or intermediate risk of pancreatic fistula after pancreaticoduodenectomy: a multicenter, randomized controlled trial[J]. Ann Surg, 2022, 275(2): e307-e314.
|
| [17] |
Liu Q F, Dai M H, Guo J C, et al. Long-term survival, quality of life, and molecular features of the patients with solid pseudopapillary neoplasm of the pancreas: a retrospective study of 454 cases[J]. Ann Surg, 2023, 278(6): 1009-1017. DOI: 10.1097/SLA.0000000000005842
|
| [18] |
沈鸣雁, 卢芳燕, 王仁芳, 等. 针对胰腺癌患者的多学科专业化护理实践与成效[J]. 中华护理杂志, 2016, 51(5): 542-546. https://www.cnki.com.cn/Article/CJFDTOTAL-ZHHL201605009.htm
Shen M Y, Lu F Y, Wang R F, et al. Effectiveness of nursing care of patients with pancreatic cancer conducted by multidisciplinary team[J]. Chin J Nurs, 2016, 51(5): 542-546. https://www.cnki.com.cn/Article/CJFDTOTAL-ZHHL201605009.htm
|
| [1] | XU Kexin, LI Guozhuang, WU Zhihong, ZHANG Jianguo, DISCO(Deciphering Disorders Involving Scoliosis & Comorbidities) Study Group, WU Nan. Progress in Clinical Diagnosis and Management of Short Stature in Ehlers-Danlos Syndromes[J]. Medical Journal of Peking Union Medical College Hospital, 2025, 16(1): 163-170. DOI: 10.12290/xhyxzz.2024-0173 |
| [2] | TIAN Kunling, CHEN Chuanning. Notch Signaling Pathway and Congenital Heart Disease[J]. Medical Journal of Peking Union Medical College Hospital, 2024, 15(3): 649-654. DOI: 10.12290/xhyxzz.2023-0594 |
| [3] | Rare Diseases Society of Chinese Research Hospital Association, National Rare Diseases Committee, Beijing Rare Disease Diagnosis, Treatment and Protection Society, Gitelman Syndrome Consensus Working Group. Expert Consensus for the Diagnosis and Treatment of Gitelman Syndrome in China (2021)[J]. Medical Journal of Peking Union Medical College Hospital, 2021, 12(6): 902-912. DOI: 10.12290/xhyxzz.2021-0555 |
| [4] | Xi BAI, Hui-juan ZHU, Hui PAN. The Multidisciplinary Pituitary Team of Peking Union Medical College Hospital: 40 Years of Hard Work[J]. Medical Journal of Peking Union Medical College Hospital, 2020, 11(3): 334-338. DOI: 10.3969/j.issn.1674-9081.20200060 |
| [5] | Yan-meng QI, Ye-cheng LIU, Hua-dong ZHU. Predictive Value of Ranson Score for Typing Moderately Severe and Severe Hyperlipidemic Acute Pancreatitis[J]. Medical Journal of Peking Union Medical College Hospital, 2019, 10(5): 489-493. DOI: 10.3969/j.issn.1674-9081.2019.05.011 |
| [6] | Hao GUO, Wen-da WANG, Yi CAI, Yu-shi ZHANG. Progress in Research on MicroRNA in Tuberous Sclerosis Complex Related Diseases[J]. Medical Journal of Peking Union Medical College Hospital, 2017, 8(4-5): 283-288. DOI: 10.3969/j.issn.1674-9081.2017.05.017 |
| [9] | Xiao-hua SHI, Zhi-yong LIANG, Huan-wen WU, Xin-yu REN, Tong-hua LIU. Effect of RNA Interference Plasmid on the Expression of Oncogene AKT2 in Pancreatic Cancer Cell Line Panc-1[J]. Medical Journal of Peking Union Medical College Hospital, 2012, 3(1): 102-108. DOI: 10.3969/j.issn.1674-9081.2012.01.021 |
| [10] | Xin-yu REN, Yu-feng YIN, Jie GAO, Sha-fei WU, Ke WANG, Wen-ze WANG, Xuan ZENG, Zhi-yong LIANG. Detection of HER2/neu Gene in Pancreatic and Gastric Adenocarcinoma among Chinese Patients[J]. Medical Journal of Peking Union Medical College Hospital, 2012, 3(1): 21-25. DOI: 10.3969/j.issn.1674-9081.2012.01.006 |
| 1. |
张佳洁，陈家伟，石婷，黄勤瑾，周依群，唐琦，张瑶瑾. 改良型加速康复护理在老年胰腺癌患者围手术期的临床应用. 老年医学与保健. 2024(05): 1348-1353 .
|
Supported by: Beijing Renhe Information Technology Co., Ltd. 
Submit
Review
Office
Email Alert
RSS
DownLoad: