Volume 14 Issue 4
Jul.  2023
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Article Contents
LIU Zhikai, CHENG Weishi, WU Wangsuo, LIANG Tianjiao, XING Qingzi, ZHANG Zizhu, LIU Zhibo, LIU Yuanhao, PAN Jianji, ZHU Shaihong, LI Qingnuan, ZHANG Fuquan, QIU Jie, HUO Li. Principles and Clinical Applications of Boron Neutron Capture Therapy[J]. Medical Journal of Peking Union Medical College Hospital, 2023, 14(4): 698-705. doi: 10.12290/xhyxzz.2023-0120
Citation: LIU Zhikai, CHENG Weishi, WU Wangsuo, LIANG Tianjiao, XING Qingzi, ZHANG Zizhu, LIU Zhibo, LIU Yuanhao, PAN Jianji, ZHU Shaihong, LI Qingnuan, ZHANG Fuquan, QIU Jie, HUO Li. Principles and Clinical Applications of Boron Neutron Capture Therapy[J]. Medical Journal of Peking Union Medical College Hospital, 2023, 14(4): 698-705. doi: 10.12290/xhyxzz.2023-0120

Principles and Clinical Applications of Boron Neutron Capture Therapy

doi: 10.12290/xhyxzz.2023-0120
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  • Corresponding author: HUO Li, E-mail: huoli@pumch.cn
  • Received Date: 2023-03-10
  • Accepted Date: 2023-04-03
  • Available Online: 2023-04-04
  • Publish Date: 2023-07-30
  • Boron neutron capture therapy (BNCT) is an advanced radiation therapy technique that is rapidly developing in the field of cancer treatment. This technique, an atomic-level binary targeted therapy, kills cancer cells by causing a 10B(n, α)7Li nuclear reaction within the cancer cells, and its clinical implementation requires professional technology and device support. The core elements of BNCT include appropriate neutron sources and neutron capture drugs. Compared with traditional radiotherapy techniques, BNCT shows outstanding advantages in treating locally recurrent tumors, such as central nervous system tumors and head and neck tumors. Furthermore, it can better protect normal organs, especially for tumors that have already significantly invaded surrounding organs, demonstrating its promising future prospects. This article mainly elaborates on the technical principles, core elements, and clinical applications of BNCT, in hope of providing reference for clinical diagnosis and treatment.
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