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Volume 14 Issue 5
Sep.  2023
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GAO Luyang, LUO Qin, ZHAO Zhihui, ZHAO Qing, LIU Zhihong. Advances in Balloon Pulmonary Angioplasty for the Treatment of Chronic Thromboembolic Pulmonary Hypertension[J]. Medical Journal of Peking Union Medical College Hospital, 2023, 14(5): 1060-1066. DOI: 10.12290/xhyxzz.2023-0031
Citation: GAO Luyang, LUO Qin, ZHAO Zhihui, ZHAO Qing, LIU Zhihong. Advances in Balloon Pulmonary Angioplasty for the Treatment of Chronic Thromboembolic Pulmonary Hypertension[J]. Medical Journal of Peking Union Medical College Hospital, 2023, 14(5): 1060-1066. DOI: 10.12290/xhyxzz.2023-0031
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Advances in Balloon Pulmonary Angioplasty for the Treatment of Chronic Thromboembolic Pulmonary Hypertension

  • Fuwai Hospital, National Center for Cardiovascular Diseases, National Clinical Research Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100037, China

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  • Corresponding author:

    LIU Zhihong, E-mail: zhihongliufuwai@163.com

  • Received Date: January 11, 2023
  • Accepted Date: February 08, 2023
  • Issue Publish Date: September 29, 2023
    Graphical Abstract
    • Abstract
  • Chronic thromboembolic pulmonary hypertension (CTEPH) is a chronic life-threatening disease caused by organized blood clots that narrow or block the pulmonary arteries, leading to redistributions of blood flow and remodeling of the pulmonary microvascular bed. This progressive increase in pulmonary vascular resistance and pulmonary arterial pressure eventually results in right heart failure or even death. Pulmonary endarterectomy (PEA) is considered the preferred treatment for CTEPH. However, approximately 40% of patients are unable to undergo PEA surgery due to distal lesions or complications. Balloon pulmonary angioplasty (BPA) is an angiographically guided catheter intervention that uses appropriately sized balloons to dilate and open narrowed or occluded pulmonary vessels step by step. BPA holds great promise for offering a new treatment option for these patients. This article reviews the clinical efficacy and predictability of postoperative complications of BPA in treating CTEPH, as well as the advances in combined treatment of BPA with PEA or with riociguat, with the aim to provide reference for clinicians in selecting treatment options for CTEPH patients.
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    • References (52)
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