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Volume 13 Issue 6
Nov.  2022
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LUO Jichang, WANG Tao, JIAO Liqun. Treatment of Intracranial Atherosclerotic Stenosis: Current Debates and Future Directions[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(6): 907-914. DOI: 10.12290/xhyxzz.2022-0592
Citation: LUO Jichang, WANG Tao, JIAO Liqun. Treatment of Intracranial Atherosclerotic Stenosis: Current Debates and Future Directions[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(6): 907-914. DOI: 10.12290/xhyxzz.2022-0592
shu

Treatment of Intracranial Atherosclerotic Stenosis: Current Debates and Future Directions

  • 1.

    Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, China International Neuroscience Institute, Beijing 100053, China

  • 2.

    Department of Interventional Radiology, Xuanwu Hospital, Capital Medical University, China International Neuroscience Institute, Beijing 100053, China

Funds: 

the 12th Five-year Plan for National Key Research and Development Program of China 2011BAI08B04

the 13th Five-year Plan for National Key Research and Development Program of China 2016YFC1301703

More Information
  • Corresponding author:

    JIAO Liqun, E-mail: liqunjiao@sina.cn

  • Received Date: October 11, 2022
  • Accepted Date: October 19, 2022
  • Available Online: October 25, 2022
  • Issue Publish Date: November 29, 2022
    Graphical Abstract
    • Abstract
  • Intracranial atherosclerotic stenosis (ICAS) is a leading cause of ischemic stroke, especially in Asia. Since the publication of high-quality randomized controlled trials conducted by the United States in 2011, ICAS has been a subject of controversy and concerns. Recently, the results of a randomized controlled trial published in the leading international medical journal compare the effectiveness of endovascular treatment and medical treatment for ICAS in the Chinese population, which has reattracted public attention to this issue. Endovascular therapy is not inferior to medical treatment, and the benefits of endovascular therapy may be greater in drug-refractory patients with hemodynamic disorders.Therefore, this paper systematically discusses ICAS disease characteristics, treatment status, and future directions, suggesting that endovascular therapy may be of further benefit to drug-refractory patients with hemodynamic disorders, and stricter medical management and improved patient compliance will further reduce stroke recurrences and mortality.
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