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Volume 13 Issue 6
Nov.  2022
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DUAN Anqi, LUO Qin, ZHAO Zhihui, ZHAO Qing, LIU Zhihong. Right Ventricular-pulmonary Arterial Coupling in Pulmonary Hypertension: Application Advances[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(6): 1051-1056. DOI: 10.12290/xhyxzz.2021-0797
Citation: DUAN Anqi, LUO Qin, ZHAO Zhihui, ZHAO Qing, LIU Zhihong. Right Ventricular-pulmonary Arterial Coupling in Pulmonary Hypertension: Application Advances[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(6): 1051-1056. DOI: 10.12290/xhyxzz.2021-0797
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Right Ventricular-pulmonary Arterial Coupling in Pulmonary Hypertension: Application Advances

  • Center for Pulmonary Vascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, National Center for Cardiovascular Disease, Beijing 100037, China

Funds: 

CAMS Innovation Fund for Medical Sciences 2020-I2M-C&T-B-055

Beijing Municipal Natural Science Foundation 7202168

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  • Corresponding author:

    LIU Zhihong, E-mail: zhihongliufuwai@163.com

  • Received Date: December 22, 2021
  • Accepted Date: February 08, 2022
  • Available Online: November 06, 2022
  • Issue Publish Date: November 29, 2022
    Graphical Abstract
    • Abstract
  • Prognosis in pulmonary hypertension is closely associated with right heart function. In the early stage of pulmonary hypertension, the right ventricle can maintain the normal blood flow of the pulmonary circulation by increasing its contractility. As the disease progresses, the right ventricular afterload rises persistently, the right ventricle is gradually decompensated, even right heart failure occurs. Right ventricular-pulmonary arterial coupling refers to a matching between right ventricular contractility and afterload. The impairment of this coupling may be an early marker of right ventricular dysfunction. This article reviews the research progress of its assessment and application in pulmonary hypertension.
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    • References (41)
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