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Volume 13 Issue 1
Jan.  2022
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CHEN Xiaojun, LIU Yanquan, HU Xiaomei, HUANG Surong, SHEN Jianzhen. Regimen of Azacitidine Combined with GemOx in the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm: A Case Report[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(1): 124-129. DOI: 10.12290/xhyxzz.2021-0465
Citation: CHEN Xiaojun, LIU Yanquan, HU Xiaomei, HUANG Surong, SHEN Jianzhen. Regimen of Azacitidine Combined with GemOx in the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm: A Case Report[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(1): 124-129. DOI: 10.12290/xhyxzz.2021-0465
shu

Regimen of Azacitidine Combined with GemOx in the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm: A Case Report

  • 1.

    Department of Hematology, Fujian Institute of Hematology, National Key Laboratory of Hematology, Fujian Medical University Union Hospital, Fuzhou 350001, China

  • 2.

    Department of Oncology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi 341000, China

  • 3.

    Department of Pathology, Fujian Medical University Union Hospital, Fuzhou 350001, China

Funds: 

National Natural Science Foundation of China 81300428

Fujian Blood Medical Center Construction Project Fujian Mdical Administration[2017] No. 171

National and Fujian Provincial Key Clinical Specialty Construction Project Fujian Mdical Letter[2011] No. 1018

National and Fujian Provincial Key Clinical Specialty Construction Project Fujian Health Science and Education[2012] No. 149

More Information
  • Corresponding author:

    SHEN Jianzhen, E-mail: doctorsjz@163.com

  • Received Date: June 11, 2021
  • Accepted Date: July 28, 2021
  • Available Online: September 14, 2021
  • Issue Publish Date: January 29, 2022
    Graphical Abstract
    • Abstract
  • Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a highly malignant hematological tumor derived from the precursor cells of plasmacytoid dendritic cells. BPDCN that primarily originates in the nasal cavity is clinically rare and easily misdiagnosed or missed. At present, there is no standard treatment for BPDCN in China and abroad. This article reported a female patient with BPDCN primarily in the nasal cavity. The regimen of Azacitidine combined with GemOx had a good clinical effect on this patient and significantly controlled the condition and improved the clinical symptoms. This article analyzed and discussed the clinical diagnosis and treatment of this patient, aiming to improve clinicians' understanding of rare BPDCN.
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    • References (21)
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