The Role of Patent Foramen Ovale Closure in the Prevention of Stroke: Development in Foreign Countries and Status in China

After nearly 20 years of intense debate and a large number of studies, the role of patent foramen ovale (PFO) closure in the secondary prevention of stroke has been determined. This article starts with evidence-based medicine and elaborates the research results of transcatheter closure of PFO to prevent stroke in recent years domestically and abroad, aiming to clarify which types of PFO population can benefit from closure treatment.