Email Alert RSS
Volume 12 Issue 3
May  2021
Turn off MathJax
Article Contents
Abstract
References
Related Articles
LUO Pan, XU Yang. Correlation Between Gastric Polyps and Helicobacter Pylori Infection[J]. Medical Journal of Peking Union Medical College Hospital, 2021, 12(3): 391-395. DOI: 10.12290/xhyxzz.20200074
Citation: LUO Pan, XU Yang. Correlation Between Gastric Polyps and Helicobacter Pylori Infection[J]. Medical Journal of Peking Union Medical College Hospital, 2021, 12(3): 391-395. DOI: 10.12290/xhyxzz.20200074
shu

Correlation Between Gastric Polyps and Helicobacter Pylori Infection

  • Department of Gastroenterology, the Second Xiangya Hospital of Central South University, Changsha 410011, China

More Information
  • Corresponding author:

    XU Yang Tel: 86-731-85295149, E-mail: 13808432219xy@sina.com

  • Received Date: March 10, 2020
  • Accepted Date: April 15, 2020
  • Issue Publish Date: May 29, 2021
    Graphical Abstract
    • Abstract
  • Gastric polyps are one of the common lesions found in endoscopy, which have malignant potential. Its occurrence is related to many factors. The specific etiology and pathogenesis of gastric polyps are still unclear. Studies have found that certain pathological types of gastric polyps are related to Helicobacter pylori(Hp)infection. Hp-eradication therapy has a significantly preventive effect on partial hyperplastic polyps and adenomatous polyps, while gastric fundus polyps are negatively correlated with Hp infection. It is important to clarify the correlation between gastric polyps and Hp infection, as well as the impact of Hp-eradication treatment on various pathological types of gastric polyps. In this paper, we will review the relationship between gastric polyps and Hp infection to provide the basis for the clinical management of gastric polyps and Hp infection.
    • FullText(HTML)
    • References (39)
  • [1]
    Goddard AF, Badreldin R, Pritchard DM, et al. The management of gastric polyps[J]. Gut, 2010, 59: 1270-1276. DOI: 10.1136/gut.2009.182089
    [2]
    Argüello Viúdez L, Córdova H, Uchima H, et al. Gastric polyps: Retrospective analysis of 41, 253 upper endoscopies[J]. Gastroenterol Hepatol, 2017, 40: 507-514. DOI: 10.1016/j.gastrohep.2017.01.003
    [3]
    Carmack SW, Genta RM, Schuler CM, et al. The current spectrum of gastric polyps: a 1-year national study of over 120, 000 patients[J]. Am J Gastroenterol, 2009, 104: 1524-1532. DOI: 10.1038/ajg.2009.139
    [4]
    Nam SY, Park BJ, Ryu KH, et al. Effect of Helicobacter pylori infection and its eradication on the fate of gastric polyps[J]. Eur J Gastroenterol Hepatol, 2016, 28: 449-454. DOI: 10.1097/MEG.0000000000000553
    [5]
    Sukuzi S, Gotoda T, Sukuzi H, et al. Morphologic and Histologic Changes in Gastric Adenomas After Helicobacter pylori Eradication: A Long-Term Prospective Analysis[J]. Helicobactor, 2015, 20: 431-437. DOI: 10.1111/hel.12218
    [6]
    Haumaier F, Sterlacci W, Vieth M. Histological and molecular classification of gastrointestinal polyps[J]. Best Pract Res Clin Gastroenterol, 2017, 31: 369-379. DOI: 10.1016/j.bpg.2017.06.005
    [7]
    Markowski AR, Markowska A, Guzinska-Ustymowicz K. Pathophysiological and clinical aspects of gastric hyperplastic polyps[J]. World J Gastroenterol, 2016, 22: 8883-8891. DOI: 10.3748/wjg.v22.i40.8883
    [8]
    Castro R, Pimentel-Nunes P, Dinis-Ribeiro M. Evaluation and management of gastric epithelial polyps[J]. Best Pract Res Clin Gastroenterol, 2017, 31: 381-387. DOI: 10.1016/j.bpg.2017.06.001
    [9]
    何金龙, 陈磊, 代剑华, 等. 10137例胃息肉的临床及病理特征分析[J]. 第三军医大学学报, 2018, 40: 248-254. https://www.cnki.com.cn/Article/CJFDTOTAL-DSDX201803012.htm

    He JL, Chen L, Dai JH, et al. Clinical and pathological characteristics of gastric polyps: a report of 10 137 patients[J]. Di San Jun Yi Da Xue Xue Bao, 2018, 40: 248-254. https://www.cnki.com.cn/Article/CJFDTOTAL-DSDX201803012.htm
    [10]
    Horvath B, Pai RK. Prevalence of Helicobacter pylori in Gastric Hyperplastic Polyps[J]. Int J Surg Pathol, 2016, 24: 704-708. DOI: 10.1177/1066896916648380
    [11]
    Hu HY, Zhang Q, Chen GY, et al. Risk factors and clinical correlates of neoplastic transformation in gastric hyperplastic polyps in Chinese patients[J]. Sci Rep, 2020, 10: 2582. DOI: 10.1038/s41598-020-58900-z
    [12]
    Fukuda M, Ishigaki H, Sugimoto M, et al. Histological analysis of fundic gland polyps secondary to PPI therapy[J]. Histopathology, 2019, 75: 537-545. DOI: 10.1111/his.13902
    [13]
    Sonnenberg A, Genta RM. Prevalence of benign gastric polyps in a large pathology database[J]. Dig Liver Dis, 2015, 47: 164-169. DOI: 10.1016/j.dld.2014.10.004
    [14]
    Fan NN, Yang J, Sun G, et al. Changes in the spectrum of gastric polyps in the Chinese population[J]. World J Gastroenterol, 2015, 21: 9758-9764. DOI: 10.3748/wjg.v21.i33.9758
    [15]
    Martin FC, Chenevix-Trench G, Yeomans ND. Systematic review with meta-analysis: fundic gland polyps and proton pump inhibitors[J]. Aliment Pharmacol Ther, 2016, 44: 915-925. DOI: 10.1111/apt.13800
    [16]
    Mitsui Y, Miyoshi A, Okamoto K, et al. Different pheno-types of gastric fundic gland polyposis and cancer in patients with familial adenomatous polyposis depending on Helicobacter pylori infection[J]. Gastric Cancer, 2019, 22: 1294-1300. DOI: 10.1007/s10120-019-01005-y
    [17]
    Park DY, Lauwers GY. Gastric polyps: classification and management[J]. Arch Pathol Lab Med, 2008, 132: 633-640. DOI: 10.5858/2008-132-633-GPCAM
    [18]
    Olmez S, Sayar S, Saritas B, et al. Evaluation of patients with gastric polyps[J]. North Clin Istanb, 2018, 5: 41-46. http://www.ncbi.nlm.nih.gov/pubmed/29607431
    [19]
    Çiyiltepe H, Çetin DA, Gündeş E, et al. Endoscopic and Histopathological features of the upper gastrointestinal system polyps: evaluation of 12.563 procedures[J]. Turk J Surg, 2019, 35: 98-104. DOI: 10.5578/turkjsurg.4155
    [20]
    Velázquez-Dohorn ME, López-Durand CF, Gamboa-Domínguez A. Changing Trends in Gastric Polyps[J]. Rev Invest Clin, 2018, 70: 40-45. http://europepmc.org/abstract/MED/29513301
    [21]
    Elhanafi S, Saadi M, Lou W, et al. Gastric polyps: Association with Helicobacter pylori status and the pathology of the surrounding mucosa, a cross sectional study[J]. World J Gastrointest Endosc, 2015, 7: 995-1002. DOI: 10.4253/wjge.v7.i10.995
    [22]
    Ji F, Wang ZW, Ning JW, et al. Effect of drug treatment on hyperplastic gastric polyps infected with Helicobacter pylori: a randomized, controlled trial[J]. World J Gastroenterol, 2006, 12: 1770-1773. DOI: 10.3748/wjg.v12.i11.1770
    [23]
    Nam SY, Park BJ, Ryu KH, et al. Effect of Helicobacter pylori eradication on the regression of gastric polyps in National Cancer Screening Program[J]. Korean J Intern Med, 2018, 33: 506-511. DOI: 10.3904/kjim.2016.286
    [24]
    Tokunaga K, Tanaka A, Takahashi S. Gastric hyperplastic polyps and H. pylori infection, their relationship and effects of eradication therapy[J]. Nihon Rinsho, 2013, 71: 1449-1452. http://europepmc.org/abstract/med/23967678
    [25]
    Nam SY, Lee SW, Jeon SW, et al. Helicobacter pylori Eradication Regressed Gastric Hyperplastic Polyp: A Randomized Controlled Trial[J]. Dig Dis Sci, 2020, 65: 3652-3659. DOI: 10.1007/s10620-020-06065-0
    [26]
    Yu FF, Guo YB, Wang H, et al. Type 2 diabetes mellitus and risk of colorectal adenoma: a meta-analysis of observational studies[J]. BMC Cancer, 2016, 16: 642. DOI: 10.1186/s12885-016-2685-3
    [27]
    ASGE Standards of Practice Committee, Evans JA, Chandrasekhara V, et al. The role of endoscopy in the manage-ment of premalignant and malignant conditions of the stomach[J]. Gastrointest Endosc, 2015, 82: 1-8. DOI: 10.1016/j.gie.2015.03.1967
    [28]
    Forté E, Petit B, Walter T, et al. Risk of neoplastic change in large gastric hyperplastic polyps and recurrence after endoscopic resection[J]. Endoscopy, 2020, 52: 444-453. DOI: 10.1055/a-1117-3166
    [29]
    Kang KH, Hwang SH, Kim D, et al. The Effect of Helicobacter pylori Infection on Recurrence of Gastric Hyperplastic Polyp after Endoscopic Removal[J]. Korean J Gastroenterol, 2018, 71: 213-218. DOI: 10.4166/kjg.2018.71.4.213
    [30]
    Kountouras J, Polyzos SA, Katsinelos P, et al. Potential molecular aspects of Helicobacter pylori-related hyperplastic polyp development and progression[J]. Eur J Gastroenterol Hepatol, 2016, 28: 851-852. DOI: 10.1097/MEG.0000000000000625
    [31]
    中华医学会消化病学分会幽门螺杆菌和消化性溃疡学组, 全国幽门螺杆菌研究协作组, 刘文忠, 等. 第五次全国幽门螺杆菌感染处理共识报告[J]. 中华消化杂志, 2017, 37: 364-378. DOI: 10.3760/cma.j.issn.0254-1432.2017.06.002
    [32]
    Yu XJ, Wang ZQ, Wang LL, et al. Gastric hyperplastic polyps inversely associated with current Helicobacter pylori infection[J]. Exp Ther Med, 2020, 19: 3143-3149. http://www.ingentaconnect.com/content/sp/etm/2020/00000019/00000004/art00090
    [33]
    Fixa B, Vanásek T, Volfová M, et al. Cystic polyposis of the stomach (fundic gland polyps)- relationship to the absence of Helicobacter pylori infection and a therapy with drugs suppressing gastric acidity[J]. Cas Lek Cesk, 2012, 151: 196-200. http://europepmc.org/abstract/MED/22679686
    [34]
    Cao HL, Qu R, Zhang ZH, et al. Sporadic fundic gland polyps are not associated with proton pump inhibitors therapy but negatively correlate with Helicobacter pylori infection in China[J]. Chin Med J(Engl), 2014, 127: 1239-1243. http://d.wanfangdata.com.cn/Periodical/zhcmj201407008
    [35]
    林琳, 吴静, 刘揆亮, 等. 胃底腺息肉的临床和内镜特征分析[J]. 中国内镜杂志, 2017, 23: 26-29. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGNJ201702007.htm

    Lin L, Wu J, Liu KL, et al. Clinical and endoscopic characteristics of fundic gland polyps[J]. Zhongguo Nei Jing Za Zhi, 2017, 23: 26-29. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGNJ201702007.htm
    [36]
    Notsu T, Adachi K, Mishiro T, et al. Fundic gland polyp prevalence according to Helicobacter pylori infection status[J]. J Gastroenterol Hepatol, 2020, 35: 1158-1162. DOI: 10.1111/jgh.14934
    [37]
    Cats A, Schenk BE, Bloemena E, et al. Parietal cell protru-sions and fundic gland cysts during omeprazole maintenance treatment[J]. Hum Pathol, 2000, 31: 684-690. DOI: 10.1053/hupa.2000.7637
    [38]
    Kitamura Y, Ito M, Matsuo T, et al. Characteristic epithe-lium with low-grade atypia appears on the surface of gastric cancer after successful Helicobacter pylori eradication therapy[J]. Helicobacter, 2014, 19: 289-295. DOI: 10.1111/hel.12132
    [39]
    Bae SE, Jung HY, Kang J, et al. Effect of Helicobacter pylori eradication on metachronous recurrence after endoscopic resection of gastric neoplasm[J]. Am J Gastroenterol, 2014, 109: 60-67. DOI: 10.1038/ajg.2013.404
    • Related Articles

  • Related Articles

    [1]CHEN Chen, WU Ying, HUA Xian, LU Jinnan, LI Yi, ZHAO Chunhua, MIN Han. Influence of Host Factors on Drug Resistance of Helicobacter Pylori Infection[J]. Medical Journal of Peking Union Medical College Hospital, 2024, 15(5): 1091-1099. DOI: 10.12290/xhyxzz.2024-0011
    [2]SUN Zhencan, ZHOU Jukun, XU Yunpeng, WANG Jun, ZHENG Ya, WANG Yuping, JI Rui. Mechanism of Epithelial-mesenchymal Transition Leading to Gastric Cancer Induced by Helicobacter pylori[J]. Medical Journal of Peking Union Medical College Hospital, 2024, 15(1): 160-165. DOI: 10.12290/xhyxzz.2023-0341
    [3]CHEN Danni, WANG Shiling, LU Hong, ZHENG Ya, WANG Yuping, REN Qian. Relationship and Potential Mechanism Between Helicobacter Pylori Infection and Non-alcoholic Fatty Liver Disease[J]. Medical Journal of Peking Union Medical College Hospital, 2023, 14(4): 833-838. DOI: 10.12290/xhyxzz.2022-0710
    [4]WU Guobing, CHENG Xiaolong, YU Xiao, ZHANG Aibin, LIU Min, CHEN Zhaofeng. Research Progress on the Relationship Between Helicobacter Pylori Associated Chronic Atrophic Gastritis and Gastric Cancer[J]. Medical Journal of Peking Union Medical College Hospital, 2023, 14(2): 339-345. DOI: 10.12290/xhyxzz.2022-0374
    [5]SU Pengfei, YU Jianchun. Progress in the Research on the Role of Tumor-associated Macrophages in Drug-resistance and Treatment of Tumors[J]. Medical Journal of Peking Union Medical College Hospital, 2022, 13(3): 480-486. DOI: 10.12290/xhyxzz.2021-0605
    [6]Rare Diseases Society of Chinese Research Hospital Association, National Rare Diseases Committee, Beijing Rare Disease Diagnosis, Treatment and Protection Society, Gitelman Syndrome Consensus Working Group. Expert Consensus for the Diagnosis and Treatment of Gitelman Syndrome in China (2021)[J]. Medical Journal of Peking Union Medical College Hospital, 2021, 12(6): 902-912. DOI: 10.12290/xhyxzz.2021-0555
    [7]Nian-sheng YANG. Trends in the Pharmacological Treatment for Systemic Lupus Erythematosus[J]. Medical Journal of Peking Union Medical College Hospital, 2020, 11(3): 247-251. DOI: 10.3969/j.issn.1674-9081.20200061
    [8]Min YAO, Yan-mei LI. Effect of the Quadruple Therapy of Eradicating Helicobacter Pylori on Gastrointestinal Microecology[J]. Medical Journal of Peking Union Medical College Hospital, 2019, 10(3): 268-271. DOI: 10.3969/j.issn.1674-9081.2019.03.014
    [9]Yan KANG. Treatments of Sepsis and Septic Shock: Advancements in Controversy[J]. Medical Journal of Peking Union Medical College Hospital, 2018, 9(5): 421-425. DOI: 10.3969/j.issn.1674-9081.2018.05.009
    [10]Ming-sheng MA, Xü-de ZHANG, Min WEI, Shi-min ZHAO, Zheng-qing QIU. Efficacy of Low Dose Corticosteroid Therapy in Duchenne Muscular Dystrophy[J]. Medical Journal of Peking Union Medical College Hospital, 2014, 5(4): 384-388. DOI: 10.3969/j.issn.1674-9081.2014.04.006

  • Cited by

    Periodical cited type(5)

    1. 张益宇，方向明. 胃息肉与幽门螺杆菌感染关系的研究进展. 临床内科杂志. 2023(04): 284-286 .
    2. 蒋琦 ，刘卫东 ，惠文佳 ，高峰 . 胃腺瘤性息肉内镜病理特点及癌变特征分析. 现代消化及介入诊疗. 2023(02): 173-176 .
    3. 邢晓丹，朱燃. 51例胃多发白色扁平隆起性病变患者的临床特点分析. 黑龙江医学. 2023(21): 2569-2571 .
    4. 姜莹，赵蜀坪，蔡丽君. 胃息肉发生的相关因素调查研究. 光明中医. 2022(24): 4426-4429 .
    5. 仇娇敏，韦兴静，崔立，王军. 胃息肉患者PGI、PGII、G-17的临床变化及与Hp感染研究. 系统医学. 2022(20): 1-4 .

    Other cited types(4)

Catalog

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (553) PDF downloads (33) Cited by(9)
    Related
    Links: National Health Commission of the People's Republic of China Chinese Academy of Medical Sciences(CAMS) AMLC Check CNKI Database CNKI Term Online Chinese General Practice
    Address：Room 302,Third Floor,Building 7, No. 1 Shuaifuyuan, Wangfujing, Dongcheng District, Beijing 100730, China
    Tel：010-69154261/4262
    E - mail：medj@pumch.cn mjpumch@126.com
    Copyright of website：Editorial Office of Medical Journal of Peking Union Medical College Hospital

    Supported by: Beijing Renhe Information Technology Co., Ltd.  Baidu Analytics

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return
    x Close Forever Close