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胃底腺息肉与质子泵抑制剂及胃癌的相关性

黄诗琴,  徐杨

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文章导航 > 协和医学杂志  > 2021 >  12(2): 249-253
黄诗琴, 徐杨. 胃底腺息肉与质子泵抑制剂及胃癌的相关性[J]. 协和医学杂志, 2021, 12(2): 249-253. doi: 10.3969/j.issn.1674-9081.2020.00.016
引用本文: 黄诗琴, 徐杨. 胃底腺息肉与质子泵抑制剂及胃癌的相关性[J]. 协和医学杂志, 2021, 12(2): 249-253. doi: 10.3969/j.issn.1674-9081.2020.00.016
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HUANG Shi-qin, XU Yang. Correlation of Proton Pump Inhibitors and Gastric Carcinoma with Fundic Gland Polyps[J]. Medical Journal of Peking Union Medical College Hospital, 2021, 12(2): 249-253. doi: 10.3969/j.issn.1674-9081.2020.00.016
Citation: HUANG Shi-qin, XU Yang. Correlation of Proton Pump Inhibitors and Gastric Carcinoma with Fundic Gland Polyps[J]. Medical Journal of Peking Union Medical College Hospital, 2021, 12(2): 249-253. doi: 10.3969/j.issn.1674-9081.2020.00.016
shu

胃底腺息肉与质子泵抑制剂及胃癌的相关性

doi: 10.3969/j.issn.1674-9081.2020.00.016

  • 中南大学湘雅二医院消化内科，长沙 410011

详细信息
    通讯作者:

    徐 杨  电话：0731-85295149，E-mail: 13808432219xy@sina.com

  • 中图分类号: R735.2;R573

Correlation of Proton Pump Inhibitors and Gastric Carcinoma with Fundic Gland Polyps

  • Department of Gastroenterology, the Second Xiangya Hospital of Central South University, Changsha 410011, China

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    摘要
  • 摘要: 胃底腺息肉是胃底胃体黏膜形成的单发或多发性广基息肉样隆起，是目前国内外常见的息肉类型。其最初在家族性腺瘤性息肉病患者中被发现，越来越多的报道认为胃底腺息肉与质子泵抑制剂的长期使用相关。然而，国内对于长期接受质子泵抑制剂的患者中胃底腺息肉的发生率和发展情况调查研究较少，二者是否存在联系尚存争议，且胃底腺息肉是否与胃癌相关尚不明确。本文就胃底腺息肉与质子泵抑制剂及胃癌的相关性作一综述，旨在为胃底腺息肉的管理策略提供依据，以期促进质子泵抑制剂在临床的规范应用。
    Abstract: Fundic gland polyps are single or multiple wide-based polypoid protruding lesions formed by the mucous membrane of stomach fundus and body, which are common at home and abroad. They were initially described in patients with familial adenomatous polyposis and are now increasingly reported to be associated with long-term use of proton pump inhibitors. However, no definite conclusion has been drawn on the relationship between them. There are few studies on the incidence and development of fundic gland polyps in patients receiving long-term proton pump inhibitors in China. Whether there is a correlation between the two is still controversial, and whether fundic gland polyps are related to gastric carcinoma is not clear. This paper will review the relationship between fundic gland polyps and proton pump inhibitors and its correlation with gastric carcinoma, in order to provide evidence for the management strategy of fundic gland polyps and promote the standard application of proton pump inhibitors in clinical practice.
    作者贡献：黄诗琴负责查阅文献，撰写文章；徐杨审阅、修订文章。
    利益冲突：  无
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    • 参考文献(50)
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出版历程
  • 收稿日期:  2019-11-18
  • 录用日期:  2020-08-20
  • 网络出版日期:  2020-12-01
  • 刊出日期:  2021-05-30

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