Abstract: In recent years, in the context of "Healthy China", precision medicine and biobanks have ushered in a golden period of rapid development. In the era of precision medicine, as an emerging field in the medical industry, biobanks have their own development trend and characteristics: the development process needs standardization, highly relies on information technology, is inseparable from multi-center alliance and resource sharing, and needs the support of multidisciplinary integration. With the continuous development of precision medicine, biobanks developed from its infancy stage, a platform of biological samples and information resource integration, into a service platform of precision medical study support and a platform of transformation cooperation. In addition, during the development stage of biobanks, there are problems of data security, privacy protection and sustainable operation.