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阿司匹林:关节置换术后抗凝新观念

曹时亮 任毅 冯宾

曹时亮, 任毅, 冯宾. 阿司匹林:关节置换术后抗凝新观念[J]. 协和医学杂志, 2019, 10(6): 639-646. doi: 10.3969/j.issn.1674-9081.2019.06.016
引用本文: 曹时亮, 任毅, 冯宾. 阿司匹林:关节置换术后抗凝新观念[J]. 协和医学杂志, 2019, 10(6): 639-646. doi: 10.3969/j.issn.1674-9081.2019.06.016
Shi-liang CAO, Yi REN, Bin FENG. Aspirin:A New Choice for Prevention of Venous Thromboembolism after Arthroplasty[J]. Medical Journal of Peking Union Medical College Hospital, 2019, 10(6): 639-646. doi: 10.3969/j.issn.1674-9081.2019.06.016
Citation: Shi-liang CAO, Yi REN, Bin FENG. Aspirin:A New Choice for Prevention of Venous Thromboembolism after Arthroplasty[J]. Medical Journal of Peking Union Medical College Hospital, 2019, 10(6): 639-646. doi: 10.3969/j.issn.1674-9081.2019.06.016

阿司匹林:关节置换术后抗凝新观念

doi: 10.3969/j.issn.1674-9081.2019.06.016
基金项目: 

国家自然科学基金 81871740

详细信息
    通讯作者:

    冯宾 电话:010-69152800, E-mail:fengbin@pumch.cn

  • 中图分类号: R68

Aspirin:A New Choice for Prevention of Venous Thromboembolism after Arthroplasty

More Information
  • 摘要: 静脉血栓栓塞症是关节置换术后严重并发症, 有效的术后抗凝是其最主要的预防及治疗措施。低分子肝素、Xa因子抑制剂等抗凝药物是目前预防静脉血栓栓塞症的首选药物, 虽然其疗效肯定, 出血风险较低, 但仍存在价格较高、使用及保存不便等问题。近年来, 部分指南及研究认为抗血小板药物阿司匹林同样可用于关节置换术后静脉血栓栓塞症的预防, 其与抗凝药物预防效果相似, 安全性好, 具有价格低廉、无须监测、口服方便等优点, 且小剂量阿司匹林即可有足够的预防效果。另有研究认为, 阿司匹林相比于抗凝药物, 围手术期出血风险更低。总之, 阿司匹林用于关节置换术后静脉血栓栓塞症预防疗效肯定且安全性好, 是关节置换术后抗凝药物的新选择。
    利益冲突  无
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出版历程
  • 收稿日期:  2018-01-02
  • 刊出日期:  2019-11-30

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