Abstract: The concept of enhanced recovery after surgery (ERAS) can effectively accelerate the recovery of patients after surgery, improve prognosis, reduce hospitalization costs, and thus get better medical results. According to the latest literature at home and abroad, a group of international experts on the surgical management of esophageal cancer systematically assessed the evidence level and overall recommendation of all parts based on the evaluation system. Finally, a total of 39 parts of the Guidelines for Perioperative Care in Esophagectomy:Enhanced Recovery after Surgery Society Recommendations were formulated. This is the first guidance on ERAS of esophagectomy, with a view to promoting the standardization of clinical practice of ERAS in the perioperative medical modality. This paper interprets the guidelines and explains the hot issues.