留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

光声成像技术及其临床应用

张睿 杨萌 姜玉新

张睿, 杨萌, 姜玉新. 光声成像技术及其临床应用[J]. 协和医学杂志, 2019, 10(4): 381-386. doi: 10.3969/j.issn.1674-9081.2019.04.014
引用本文: 张睿, 杨萌, 姜玉新. 光声成像技术及其临床应用[J]. 协和医学杂志, 2019, 10(4): 381-386. doi: 10.3969/j.issn.1674-9081.2019.04.014
Rui ZHANG, Meng YANG, Yu-xin JIANG. Photoacoustic Imaging and Its Clinical Applications[J]. Medical Journal of Peking Union Medical College Hospital, 2019, 10(4): 381-386. doi: 10.3969/j.issn.1674-9081.2019.04.014
Citation: Rui ZHANG, Meng YANG, Yu-xin JIANG. Photoacoustic Imaging and Its Clinical Applications[J]. Medical Journal of Peking Union Medical College Hospital, 2019, 10(4): 381-386. doi: 10.3969/j.issn.1674-9081.2019.04.014

光声成像技术及其临床应用

doi: 10.3969/j.issn.1674-9081.2019.04.014
基金项目: 

科技部科技合作专项基金 2015DFA30440

国家自然科学青年基金 81301268

北京市科技新星计划 Z131107000413063

北京市科技新星交叉合作计划 xxjc201812

详细信息
  • 中图分类号: R445.9

Photoacoustic Imaging and Its Clinical Applications

More Information
  • 摘要: 光声成像作为一种新兴的生物医学成像技术,以光声效应为成像基础,结合光学成像对比度高、光谱特异度好、声学成像空间分辨率高和穿透力强的特点,具有广泛的临床应用前景。本文从光声成像基本原理、成像模式、在临床医学领域的应用前景以及目前存在的技术局限等方面进行详细介绍。
    利益冲突  无
  • [1] Yao J, Wang LV. Photoacoustic tomography: fundamentals, advances and prospects[J]. Contrast Media Mol Imaging, 2011, 6: 332-345. doi:  10.1002/cmmi.443
    [2] 谷怀民, 杨思华, 向良忠.光声成像及其在生物医学中的应用[J].生物化学与生物物理进展, 2006, 33: 431-437. doi:  10.3321/j.issn:1000-3282.2006.05.004
    [3] 张建英, 谢文明, 曾志平, 等.光声成像技术的最新进展[J].中国光学, 2011, 4: 111-117. doi:  10.3969/j.issn.2095-1531.2011.02.003
    [4] 张振奇, 卢漫.光声成像的研究进展[J].实用医院临床杂志, 2015, 12: 139-141. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=syyylczz201502055
    [5] Valluru KS, Willmann JK. Clinical photoacoustic imaging of cancer[J]. Ultrasonography, 2016, 35:267-280. doi:  10.14366/usg.16035
    [6] Bouchard R, Sahin O, Emelianov S. Ultrasound-guided photoacoustic imaging: current state and future development[J]. IEEE Trans Ultrason Ferroelectr Freq Control, 2014, 61:450-466. doi:  10.1109/TUFFC.2014.2930
    [7] Taruttis A, Ntziachristos V. Translational optical imaging[J]. AJR Am J Roentgenol, 2012, 199: 263-271. doi:  10.2214/AJR.11.8431
    [8] 陶超, 殷杰, 刘晓峻.生物组织光声成像技术综述[J].数据采集与处理, 2015, 30: 289-298. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=sjcjycl201502006
    [9] 徐晓辉, 李晖.生物医学光声成像[J].物理, 2008, (2): 111-119. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=wl200802008
    [10] 陶超, 刘晓峻.生物医学光声成像的研究进展[J].应用声学, 2012, 31: 401-409. doi:  10.11684/j.issn.1000-310X.2012.06.001
    [11] Zhou Y, Yao J, Wang LV. Tutorial on photoacoustic tomography[J]. J Biomed Opt, 2016, 21: 61007. doi:  10.1117/1.JBO.21.6.061007
    [12] Yao J, Xia J, Wang LV. Multiscale Functional and Molecular Photoacoustic Tomography[J]. Ultrason Imaging, 2016, 38: 44-62. doi:  10.1177/0161734615584312
    [13] Wang LV, Gao L. Photoacoustic Microscopy and Computed Tomography: From Bench to Bedside[J]. Annu Rev Biomed Eng, 2014, 16: 155-185. doi:  10.1146/annurev-bioeng-071813-104553
    [14] Hu S, Wang LV. Optical-Resolution Photoacoustic Microscopy: Auscultation of Biological Systems at the Cellular Level[J]. Biophys J, 2013, 105: 841-847. doi:  10.1016/j.bpj.2013.07.017
    [15] Yang JM, Maslov K, Yang HC, et al. Photoacoustic endoscopy[J]. Opt Lett, 2009, 34: 1591-1593. doi:  10.1364/OL.34.001591
    [16] Taruttis A, van Dam GM, Ntziachristos V. Mesoscopic and Macroscopic Optoacoustic Imaging of Cancer[J]. Cancer Res, 2015, 75:1548-1559. doi:  10.1158/0008-5472.CAN-14-2522
    [17] Wilson KE, Wang TY, Willmann JK. Acoustic and photoacoustic molecular imaging of cancer[J]. J Nucl Med, 2013, 54:1851-1854. doi:  10.2967/jnumed.112.115568
    [18] 曾礼漳, 杨思华, 邢达.光声成像技术及其医学应用进展[J].华南师范大学学报(自然科学版), 2016, 48: 9-15.
    [19] Luke GP, Yeager D, Emelianov SY. Biomedical Applica-tions of Photoacoustic Imaging with Exogenous Contrast Agents [J]. Annu Rev Biomed Eng, 2012, 40: 422-437. doi:  10.1007/s10439-011-0449-4
    [20] 唐鹤文, 杨萌, 姜玉新.光声成像分子造影剂[J].协和医学杂志, 2018, 9: 358-363. doi:  10.3969/j.issn.1674-9081.2018.04.013
    [21] Zackrisson S, van de Ven SMWY, Gambhir SS. Light In and Sound Out: Emerging Translational Strategies for Photoacoustic Imaging[J]. Cancer Res, 2014, 74: 979-1004. doi:  10.1158/0008-5472.CAN-13-2387
    [22] Heijblom M, Piras D, Xia W, et al. Visualizing breast cancer using the Twente photoacoustic mammoscope: what do we learn from twelve new patient measurements?[J]. Opt Express, 2012, 20: 11582-11597. doi:  10.1364/OE.20.011582
    [23] Heijblom M, Piras D, van den Engh FM, et al. The state of the art in breast imaging using the Twente Photoacoustic Mammoscope: results from 31 measurements on malignancies[J]. Eur Radiol, 2016, 26: 3874-3887. doi:  10.1007/s00330-016-4240-7
    [24] Toi M, Asao Y, Matsumoto Y, et al. Visualization of tumor-related blood vessels in human breast by photoacoustic imaging system with a hemispherical detector array[J]. Scientific Reports, 2017, 7: 41970. doi:  10.1038/srep41970
    [25] Valluru KS, Wilson KE, Willmann JK. Photoacoustic Imaging in Oncology: Translational Preclinical and Early Clinical Experience[J]. Radiology, 2016, 280: 332-349. doi:  10.1148/radiol.16151414
    [26] Dima A, Ntziachristos V. In-vivo handheld optoacoustic tomography of the human thyroid[J]. Photoacoustics, 2016, 4:65-69. doi:  10.1016/j.pacs.2016.05.003
    [27] Dogra VS, Chinni BK, Valluru KS, et al. Preliminary results of ex vivo multispectral photoacoustic imaging in the management of thyroid cancer[J]. AJR Am J Roentgenol, 2014, 202: W552-W558. doi:  10.2214/AJR.13.11433
    [28] Levi J, Kothapalli SR, Bohndiek S, et al. Molecular photoacoustic imaging of follicular thyroid carcinoma[J]. Clin Cancer Res, 2013, 19:1494-1502. doi:  10.1158/1078-0432.CCR-12-3061
    [29] Kang J, Chung WY, Kang SW, et al. Ex vivo estimation of photoacoustic imaging for detecting thyroid microcalcifica-tions[J]. PLoS One, 2014, 9: e113358. doi:  10.1371/journal.pone.0113358
    [30] Yang M, Zhao L, He X, et al. Photoacoustic/ultrasound dual imaging of human thyroid cancers: an initial clinical study[J]. Biomed Opt Express, 2017, 8: 3449-3457. doi:  10.1364/BOE.8.003449
    [31] 黄盛松, 刘博, 吴登龙.光声成像在泌尿系疾病的研究进展[J].外科研究与新技术, 2016, 5: 49-52. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=wkyjyxjs201601016
    [32] Bayer CL, Joshi PP, Emelianov SY. Photoacoustic imaging: a potential tool to detect early indicators of metastasis[J]. Expert Rev Med Devices, 2014, 10: 125-134. https://www.ncbi.nlm.nih.gov/pubmed/23278229
    [33] Dogra VS, Chinni BK, Valluru KS, et al. Multispectral Photoacoustic Imaging of Prostate Cancer: Preliminary Ex-vivo Results[J]. J Clin Imaging Sci, 2013, 3: 41. doi:  10.4103/2156-7514.119139
    [34] Bauer DR, Olafsson R, Montilla LG, et al. 3-D photoacoustic and pulse echo imaging of prostate tumor progression in the mouse window chamber[J]. J Biomed Opt, 2011, 16: 26012. doi:  10.1117/1.3540668
    [35] Horiguchi A, Tsujita K, Irisawa K, et al. A pilot study of photoacoustic imaging system for improved real-time visualization of neurovascular bundle during radical prostatectomy[J]. Prostate, 2016, 76: 307-315. doi:  10.1002/pros.23122
    [36] Wang X, Pang Y, Ku G, et al. Noninvasive laser-induced photoacoustic tomography for structural and functional in vivo imaging of the brain[J]. Nat Biotechnol, 2003, 21:803-806. doi:  10.1038/nbt839
    [37] Yao J, Wang LV. Photoacoustic Brain Imaging: from Microscopic to Macroscopic Scales[J]. Neurophotonics, 2014, 1: 011003. doi:  10.1117/1.NPh.1.1.011003
    [38] Yao J, Wang L, Yang J, et al. High-speed label-free functional photoacoustic microscopy of mouse brain in action[J]. Nat Methods, 2015, 12: 407-410. doi:  10.1038/nmeth.3336
    [39] 陈海宇, 柯秋晴, 李志芳, 等.光声成像定量评估大鼠急性心肌缺血损伤程度的研究[J].中国激光医学杂志, 2016, 25: 8-14. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=zgjgyx201601002
    [40] 龚小竞, 孟静, 陈健桦, 等.生物医学光声成像技术及其临床应用进展[J].集成技术, 2013, 2: 53-59.
    [41] 孙正, 马晓乾.血管内超声/光声联合成像研究进展[J].中国医学影像技术, 2016, 32: 979-982. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=zgyxyxjs201606044
    [42] Sethuraman S, Aglyamov SR, Amirian JH, et al. Intravascular photoacoustic imaging using an IVUS imaging catheter[J]. IEEE Trans Ultrason Ferroelectr Freq Control, 2007, 54: 978-986. doi:  10.1109/TUFFC.2007.343
    [43] Wang B, Karpiouk A, Yeager D, et al. In vivo intravascular ultrasound-guided photoacoustic imaging of lipid in plaques using an animal model of atherosclerosis[J]. Ultrasound Med Biol, 2012, 38: 2098-2103. doi:  10.1016/j.ultrasmedbio.2012.08.006
    [44] 张智海, 刘忠厚, 李娜, 等.中国人骨质疏松症诊断标准专家共识(第三稿2014版)[J].中国骨质疏松杂志, 2014, 20: 1007-1010. doi:  10.3969/j.issn.1006-7108.2014.09.001
    [45] 封婷.光声分析方法在骨质定性和定量评估中的研究[D].南京: 南京大学, 2016.
    [46] Wang X, Chamberland DL, Carson PL, et al. Imaging of joints with laser-based photoacoustic tomography: an animal study[J]. Med Phys, 2006, 33: 2691-2697. doi:  10.1118/1.2214166
    [47] Chamberland DL, Wang X, Roessler BJ. Photoacoustic tomography of carrageenan-induced arthritis in a rat model[J]. J Biomed Opt, 2008, 13: 011005. doi:  10.1117/1.2841028
    [48] Wang X, Chamberland DL, Jamadar DA. Noninvasive photoacoustic tomography of human peripheral joints toward diagnosis of inflammatory arthritis[J]. Opt Lett, 2007, 32: 3002-3004. doi:  10.1364/OL.32.003002
    [49] Sun Y, Sobel E, Jiang H. Quantitative three-dimen-sional photoacoustic tomography of the finger joints: an in vivo study[J]. J Biomed Opt, 2009, 14: 64002. doi:  10.1117/1.3257246
    [50] Xu G, Rajian JR, Girish G, et al. Photoacoustic and ultrasound dual-modality imaging of human peripheral joints[J]. J Biomed Opt, 2013, 18: 10502.
    [51] 游珊珊, 徐钟慧, 姜玉新.肌肉骨骼超声在类风湿关节炎诊疗中的应用[J].协和医学杂志, 2017, 8: 215-220. doi:  10.3969/j.issn.1674-9081.2017.05.005
    [52] Wang LV, Hu S. Photoacoustic Tomography: In Vivo Imaging from Organelles to Organs[J]. Science, 2012, 335: 1458-1462. doi:  10.1126/science.1216210
  • 加载中
计量
  • 文章访问数:  1401
  • HTML全文浏览量:  163
  • PDF下载量:  913
  • 被引次数: 0
出版历程
  • 收稿日期:  2017-06-26
  • 刊出日期:  2019-07-30

目录

    /

    返回文章
    返回

    【温馨提醒】近日,《协和医学杂志》编辑部接到作者反映,有多名不法人员冒充期刊编辑发送见刊通知,鼓动作者添加微信,从而骗取版面费的行为。特提醒您,本刊与作者联系的方式均为邮件通知或电话,稿件进度通知邮箱为:mjpumch@126.com,编辑部电话为:010-69154261,请提高警惕,谨防上当受骗!如有任何疑问,请致电编辑部核实。谢谢!