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IgG4相关性硬化性胆管炎:肝胆胰外科医生应该重视的内科疾病

刘乔飞 刘卫 洪涛 张宁 曲强 何小东

刘乔飞, 刘卫, 洪涛, 张宁, 曲强, 何小东. IgG4相关性硬化性胆管炎:肝胆胰外科医生应该重视的内科疾病[J]. 协和医学杂志, 2019, 10(3): 201-205. doi: 10.3969/j.issn.1674-9081.2019.03.003
引用本文: 刘乔飞, 刘卫, 洪涛, 张宁, 曲强, 何小东. IgG4相关性硬化性胆管炎:肝胆胰外科医生应该重视的内科疾病[J]. 协和医学杂志, 2019, 10(3): 201-205. doi: 10.3969/j.issn.1674-9081.2019.03.003
Qiao-fei LIU, Wei LIU, Tao HONG, Ning ZHANG, Qiang QU, Xiao-dong HE. IgG4-related Sclerosing Cholangitis: An Internal Disease Calls for the Attention of Hepatic-biliary-pancreatic Surgeons[J]. Medical Journal of Peking Union Medical College Hospital, 2019, 10(3): 201-205. doi: 10.3969/j.issn.1674-9081.2019.03.003
Citation: Qiao-fei LIU, Wei LIU, Tao HONG, Ning ZHANG, Qiang QU, Xiao-dong HE. IgG4-related Sclerosing Cholangitis: An Internal Disease Calls for the Attention of Hepatic-biliary-pancreatic Surgeons[J]. Medical Journal of Peking Union Medical College Hospital, 2019, 10(3): 201-205. doi: 10.3969/j.issn.1674-9081.2019.03.003

IgG4相关性硬化性胆管炎:肝胆胰外科医生应该重视的内科疾病

doi: 10.3969/j.issn.1674-9081.2019.03.003
详细信息
    通讯作者:

    何小东 电话:010-69152611, E-mail:hexdpumch@sina.com

  • 中图分类号: R593.2

IgG4-related Sclerosing Cholangitis: An Internal Disease Calls for the Attention of Hepatic-biliary-pancreatic Surgeons

More Information
  • 摘要: IgG4相关性疾病(IgG4-related disease, IRD)是一类近10余年逐渐被认识的以血清IgG4升高、席纹状纤维化以及大量IgG4阳性浆细胞浸润为特征的多器官和系统受累的自身免疫性疾病。胆道是IRD常受累的器官之一。IgG4相关性硬化性胆管炎(IgG4 related sclerosing cholangitis, IRSC)是IRD在胆道的临床表现形式。IRSC多有胆管壁局限性增厚、胆管扩张以及梗阻性黄疸等与胆胰恶性肿瘤相类似的临床表现。IRSC对激素敏感, 预后良好, 合并恶性肿瘤罕见, 绝大多数无需手术治疗, 但近几年笔者临床工作中仍不时见到因"胆管扩张、梗阻性黄疸"行手术治疗, 术后病理证实为IRSC的病例, 回顾这些病例的诊治过程, 鲜有术前考虑IRSC的情况。临床上也可见到术前因血清IgG4升高, 起初误诊为IRSC, 错过最佳手术时机, 而术后病理证实为胆管癌的病例。故加强对IRSC的宣讲, 特别是加深肝胆胰外科医生对IRSC的认识具有重要临床意义。
    利益冲突  无
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出版历程
  • 收稿日期:  2017-08-04
  • 刊出日期:  2020-09-18

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