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感染诊疗应得到重视:支持美国感染病学会

崔娜 刘大为

崔娜, 刘大为. 感染诊疗应得到重视:支持美国感染病学会[J]. 协和医学杂志, 2018, 9(5): 417-420. doi: 10.3969/j.issn.1674-9081.2018.05.008
引用本文: 崔娜, 刘大为. 感染诊疗应得到重视:支持美国感染病学会[J]. 协和医学杂志, 2018, 9(5): 417-420. doi: 10.3969/j.issn.1674-9081.2018.05.008
Na CUI, Da-wei LIU. Attach Importance to the Diagnosis and Treatment of Infection:Stand for Infectious Disease Society of America[J]. Medical Journal of Peking Union Medical College Hospital, 2018, 9(5): 417-420. doi: 10.3969/j.issn.1674-9081.2018.05.008
Citation: Na CUI, Da-wei LIU. Attach Importance to the Diagnosis and Treatment of Infection:Stand for Infectious Disease Society of America[J]. Medical Journal of Peking Union Medical College Hospital, 2018, 9(5): 417-420. doi: 10.3969/j.issn.1674-9081.2018.05.008

感染诊疗应得到重视:支持美国感染病学会

doi: 10.3969/j.issn.1674-9081.2018.05.008
详细信息
    通讯作者:

    刘大为  电话:010-69152300, E-mail:dwliu98@163.com

  • 中图分类号: R441.9

Attach Importance to the Diagnosis and Treatment of Infection:Stand for Infectious Disease Society of America

More Information
    Corresponding author: LIU Da-wei    Tel:010-69152300, E-mail:dwliu98@163.com
  • 摘要: Sepsis是导致重症患者死亡的重要原因。近年来,随着临床和基础研究的不断发展,人们对于Sepsis定义、诊断以及治疗认识不断深入,患者病死率持续下降。每4年颁布一次并更新的“拯救Sepsis运动(Surviving Sepsis Campaign,SSC)”指南受到国际广泛重视。2016年版SSC指南,在对Sepsis和感染性休克重新定义、重新制定诊断标准的基础上,于2017年1月正式发布。然而,2017年11月,美国感染病学会(Infectious Disease Society of America, IDSA)即在其官方期刊Clin Infect Dis发表公开声明,对2016年版SSC指南中关于感染诊疗的推荐意见提出质疑。本文站在IDSA的立场,尝试从Sepsis概念、诊断及治疗3个方面解读IDSA声明,探讨Sepsis中的“感染”问题。
  • [1] Rhodes A, Evans LE, Alhazzani, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016[J]. Crit Care Med, 2017, 45: 486-552. doi:  10.1097/CCM.0000000000002255
    [2] Rhodes A, Evans LE, Alhazzani, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016[J]. Intensive Care Med, 2017, 43: 304-377. doi:  10.1007/s00134-017-4683-6
    [3] Gilbert DN, Kalil AC, Klompas M, et al. Infectious Diseases Society of America (IDSA) Position Statement: Why IDSA Did Not Endorse the Surviving Sepsis Campaign Guidelines.[J]. Clin Infect Dis, 2018, 66:1631-1635. doi:  10.1093/cid/cix997
    [4] Singer M, Deutschman CS, Seymour CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)[J]. JAMA, 2016, 315: 801-810. doi:  10.1001/jama.2016.0287
    [5] Klein Klouwenberg PM, Cremer OL, van Vught LA, et al. Likelihood of infection in patients with presumed sepsis at the time of intensive care unit admission: a cohort study[J]. Crit Care, 2015, 19: 319. doi:  10.1186/s13054-015-1035-1
    [6] Garcia RA, Spitzer ED, Beaudry J, et al. Multidisciplinary team review of best practices for collection and handling of blood cultures to determine effective interventions for increasing the yield of true-positive bacteremias, reducing contamination, and eliminating false-positive central line-associated bloodstream infections[J]. Am J Infect Control, 2015, 43: 1222-1237. doi:  10.1016/j.ajic.2015.06.030
    [7] Mermel LA, Allon M, Bouza E, et al. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America[J]. Clin Infect Dis, 2009, 49: 1-45. doi:  10.1086/599376
    [8] Kumar A, Roberts D, Wood KE, et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock[J]. Crit Care Med, 2006, 34: 1589-1596. doi:  10.1097/01.CCM.0000217961.75225.E9
    [9] Seymour CW, Foster G, Prescott HC, et al. Time to Treatment and Mortality during Mandated Emergency Care for Sepsis[J]. N Engl J Med, 2017, 376: 2235-2244. doi:  10.1056/NEJMoa1703058
    [10] National Quality Forum. NQF #0500 Severe Sepsis and Septic Shock: Management Bundle[EB/OL].http://www.quality-forum.org/WorkArea/linkit.aspx?inkIdentifier=id&ItemID=71548.
    [11] Institute for Healthcare Improvement. Severe sepsis bundles[EB/OL].http://www.ihi.org/resources/Pages/Tools/SevereSepsisBundles.aspx.
    [12] Kalil AC, Johnson DW, Lisco SJ, et al.Early Goal-Directed Therapy for Sepsis: A Novel Solution for Discordant Survival Outcomes in Clinical Trials[J]. Crit Care Med, 2017, 45: 607-614. doi:  10.1097/CCM.0000000000002235
    [13] Singer M. Antibiotics for Sepsis-Does Each Hour Really Count? Or is it Incestuous Amplification?[J]. Am J Respir Crit Care Med, 2017, 196: 800-802. doi:  10.1164/rccm.201703-0621ED
    [14] Klompas M. Monotherapy Is Adequate for Septic Shock Due to Gram-Negative Organisms[J]. Crit Care Med, 2017, 45:1930-1932. doi:  10.1097/CCM.0000000000002678
    [15] Brunkhorst FM, Oppert M, Marx G, et al. Effect of empirical treatment with moxifloxacin and meropenem vs meropenem on sepsis-related organ dysfunction in patients with severe sepsis: a randomized trial[J]. JAMA, 2012, 307: 2390-2399. doi:  10.1001/jama.2012.5833
    [16] Kalil AC, Metersky ML, Klompas M, et al. Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society[J]. Clin Infect Dis, 2016, 63: e61-e111. doi:  10.1093/cid/ciw353
    [17] Bouadma L, Luyt CE, Tubach F, et al. Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial[J]. Lancet, 2010, 375: 463-474. doi:  10.1016/S0140-6736(09)61879-1
    [18] de Jong E, van Oers JA, Beishuizen A, et al. Efficacy and safety of procalcitonin guidance in reducing the duration of antibiotic treatment in critically ill patients: a randomised, controlled, open-label trial[J]. Lancet Infect Dis, 2016, 16: 819-827. doi:  10.1016/S1473-3099(16)00053-0
    [19] Solomkin JS, Mazuski JE, Bradley JS, et al. Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America[J]. Clin Infect Dis, 2010, 50: 133-164. doi:  10.1086/649554
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出版历程
  • 收稿日期:  2018-04-03
  • 刊出日期:  2018-09-30

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