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临床生物样本库信息系统建设与发展

郭丹 杨文航 徐英春

郭丹, 杨文航, 徐英春. 临床生物样本库信息系统建设与发展[J]. 协和医学杂志, 2018, 9(1): 81-86. doi: 10.3969/j.issn.1674-9081.2018.01.015
引用本文: 郭丹, 杨文航, 徐英春. 临床生物样本库信息系统建设与发展[J]. 协和医学杂志, 2018, 9(1): 81-86. doi: 10.3969/j.issn.1674-9081.2018.01.015
Dan GUO, Wen-hang YANG, Ying-chun XU. Construction and Development of the Information System of Clinical Biobank[J]. Medical Journal of Peking Union Medical College Hospital, 2018, 9(1): 81-86. doi: 10.3969/j.issn.1674-9081.2018.01.015
Citation: Dan GUO, Wen-hang YANG, Ying-chun XU. Construction and Development of the Information System of Clinical Biobank[J]. Medical Journal of Peking Union Medical College Hospital, 2018, 9(1): 81-86. doi: 10.3969/j.issn.1674-9081.2018.01.015

临床生物样本库信息系统建设与发展

doi: 10.3969/j.issn.1674-9081.2018.01.015
基金项目: 

国家重点研发计划"华北地区中国人类遗传资源样本库集群建设" 2016YFC1201703

中国医学科学院医学与健康科技创新工程"内分泌肿瘤基础与临床研究" 2017-12M-1-001

详细信息
    通讯作者:

    徐英春 电话:010-69159766, E-mail:xycpumch@139.com

  • 中图分类号: R446.9

Construction and Development of the Information System of Clinical Biobank

More Information
  • 摘要: 随着转化医学的快速发展, 临床生物样本库的作用日益凸显, 其建设和应用日益受到关注和重视。信息管理系统是样本库的核心部分, 其建设应立足于支撑样本库的运营、管理和服务全过程, 通过建立样本信息数据采集流程、数据集成与交换系统及安全系统, 形成一体化整合数据库和公共门户网站, 实现生物样本、临床资料和分子数据等各种资源的高效管理和全面共享。
  • 图  1  Windber研究中心DW4TR数据库的结构[17]

    图  2  临床生物样本库信息系统架构

    图  3  临床生物样本库样本/信息数据采集流程示意图

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    [11] Cui W, Zheng P, Yang J, et al. Integrating clinical and biological information in a Shanghai biobank:introduction to the sample repository and information sharing platform project[J]. Biopreserv Biobank, 2015, 13:37-42. doi:  10.1089/bio.2014.0091
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    [14] Quinlan PR, Gardner S, Groves M, et al. A data-centric strategy for modern biobanking[J]. Adv Exp Med Biol, 2015, 864:165-169. http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=baf633974440f017028354e5b8d8adb7
    [15] Giffen CA, Carroll LE, Adams JT, et al. Providing contemporary access to historical biospecimen collections:development of the NHLBI biologic specimen and data repository information coordinating center (BioLINCC)[J]. Biopreserv Biobank, 2015, 13:271-279. doi:  10.1089/bio.2014.0050
    [16] McDonald SA, Ryan BJ, Brink A, et al. Automted web-based request mechanism for workflow enhancement in an academic customer-focused biorepository[J]. Biopreserv Biobank, 2012, 10:48-54. doi:  10.1089/bio.2011.0042
    [17] Hu H, Correll M, Kvecher L, et al. DW4TR:a data warehouse for translational research[J]. J Biomed Inform, 2011, 44:1004-1019. doi:  10.1016/j.jbi.2011.08.003
    [18] http://www.framinghamheartstudy.org/.
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    [22] 中国医药生物技术协会生物样本库标准(试行)[J].中国医药生物技术, 2011, 6: 71-80.
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出版历程
  • 收稿日期:  2017-08-16
  • 刊出日期:  2018-01-30

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