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对上皮样滋养细胞肿瘤的再认识

蒋芳 向阳

蒋芳, 向阳. 对上皮样滋养细胞肿瘤的再认识[J]. 协和医学杂志, 2018, 9(1): 31-35. doi: 10.3969/j.issn.1674-9081.2018.01.007
引用本文: 蒋芳, 向阳. 对上皮样滋养细胞肿瘤的再认识[J]. 协和医学杂志, 2018, 9(1): 31-35. doi: 10.3969/j.issn.1674-9081.2018.01.007
Fang JIANG, Yang XIANG. Deeper Understanding of Epithelioid Trophoblastic Tumor[J]. Medical Journal of Peking Union Medical College Hospital, 2018, 9(1): 31-35. doi: 10.3969/j.issn.1674-9081.2018.01.007
Citation: Fang JIANG, Yang XIANG. Deeper Understanding of Epithelioid Trophoblastic Tumor[J]. Medical Journal of Peking Union Medical College Hospital, 2018, 9(1): 31-35. doi: 10.3969/j.issn.1674-9081.2018.01.007

对上皮样滋养细胞肿瘤的再认识

doi: 10.3969/j.issn.1674-9081.2018.01.007
详细信息
    通讯作者:

    向阳 电话:010-69155635, E-mail:xiangy@pumch.cn

  • 中图分类号: R737.33

Deeper Understanding of Epithelioid Trophoblastic Tumor

More Information
    Corresponding author: XIANG Yang Tel:010-69155635, E-mail:xiangy@pumch.cn
  • 摘要: 上皮样滋养细胞肿瘤(epithelioid trophoblastic tumor, ETT)是一类少见的恶性滋养细胞肿瘤, 来源于绒毛膜型中间型滋养细胞。ETT的临床表现缺乏特异性, 给诊断带来很大难度, 确诊主要依靠手术病理诊断。虽然ETT生长缓慢, 但相比胎盘部位滋养细胞肿瘤, 其恶性程度明显升高, 某些ETT病例表现出侵袭性及致命的临床结局, 一旦出现转移或复发, 治疗效果通常较差。手术对于疾病的治疗有重要作用, 术后辅助化疗仍无规范可寻。不良预后因素包括:子宫多发病灶、出现子宫外病灶、距离前次妊娠间隔时间>4年以及高Ki-67指数。目前对于ETT的认识非常有限, 需要收集更多病例或进行前瞻性临床试验以指导对该疾病的诊断和治疗。
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出版历程
  • 收稿日期:  2017-05-10
  • 刊出日期:  2018-01-30

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