Abstract: Pain is one of the most common symptoms in cancer patients. Apart from causing patients to suffer from unpleasant feelings and emotional experiences, uncontrolled pain may also influence patients' function and quality of life, and may be associated with poorer prognosis. Difficulties in management of chronic cancer-related pain may be related to its complicated mechanisms, limitations of current clinical treatment and insufficient cognition of clinicians and patients. This review summarizes the definitions, classifications, evaluation and treatment principles of chronic cancer-related pain,, aiming to provide clinicians with the overall idea of pain management in adult cancer patients, emphasizing the importance of multidisciplinary management and patient education in cancer pain management.