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阻塞性睡眠呼吸暂停诱导肠道菌群失调与缺血性脑卒中:机制与研究进展

刘苗苗 岳红梅 李雅亭 许金回 武兴东 朱浩斌

刘苗苗, 岳红梅, 李雅亭, 许金回, 武兴东, 朱浩斌. 阻塞性睡眠呼吸暂停诱导肠道菌群失调与缺血性脑卒中:机制与研究进展[J]. 协和医学杂志, 2024, 15(2): 382-386. doi: 10.12290/xhyxzz.2023-0452
引用本文: 刘苗苗, 岳红梅, 李雅亭, 许金回, 武兴东, 朱浩斌. 阻塞性睡眠呼吸暂停诱导肠道菌群失调与缺血性脑卒中:机制与研究进展[J]. 协和医学杂志, 2024, 15(2): 382-386. doi: 10.12290/xhyxzz.2023-0452
LIU Miaomiao, YUE Hongmei, LI Yating, XU Jinhui, WU Xingdong, ZHU Haobin. Obstructive Sleep Apnea-induced Gut Dysbiosis and Ischaemic Stroke: Mechanism and Research Progress[J]. Medical Journal of Peking Union Medical College Hospital, 2024, 15(2): 382-386. doi: 10.12290/xhyxzz.2023-0452
Citation: LIU Miaomiao, YUE Hongmei, LI Yating, XU Jinhui, WU Xingdong, ZHU Haobin. Obstructive Sleep Apnea-induced Gut Dysbiosis and Ischaemic Stroke: Mechanism and Research Progress[J]. Medical Journal of Peking Union Medical College Hospital, 2024, 15(2): 382-386. doi: 10.12290/xhyxzz.2023-0452

阻塞性睡眠呼吸暂停诱导肠道菌群失调与缺血性脑卒中:机制与研究进展

doi: 10.12290/xhyxzz.2023-0452
基金项目: 

甘肃省科技计划 22ZD1FA00A

详细信息
    通讯作者:

    岳红梅, E-mail: yuehongmei18@sina.com

  • 中图分类号: R743;R543;R562

Obstructive Sleep Apnea-induced Gut Dysbiosis and Ischaemic Stroke: Mechanism and Research Progress

Funds: 

Science and Technology Project of Gansu Province 22ZD1FA00A

More Information
  • 摘要: 缺血性脑卒中作为一种高发病率、高死亡率、高致残率、高复发率的脑血管疾病,是导致我国中老年人残疾和死亡的重要原因。因此,识别与缺血性脑卒中相关危险因素并进行有效预防至关重要。有研究表明,阻塞性睡眠呼吸暂停是缺血性脑卒中发生的独立危险因素,但具体机制尚未明确。随着新一代测序技术的发展,研究发现阻塞性睡眠呼吸暂停可引起肠道菌群改变,而肠道菌群可能与缺血性脑卒中密切相关。因此,本文就阻塞性睡眠呼吸暂停诱导肠道菌群失调与缺血性脑卒中的相关机制进行综述,以期为阐明阻塞性睡眠呼吸暂停引起缺血性脑卒中的潜在病理机制提供依据。
    作者贡献:刘苗苗负责论文撰写;岳红梅负责选题设计及论文修订;李雅亭、许金回负责文献收集;武兴东、朱浩斌负责论文修订。
    利益冲突:所有作者均声明不存在利益冲突
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出版历程
  • 收稿日期:  2023-09-25
  • 录用日期:  2023-11-20
  • 刊出日期:  2024-03-30

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