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医学数字孪生方法及其应用

陈亚飞,  刘琼,  关双,  于亚南,  刘骏,  王思村,  王忠

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陈亚飞, 刘琼, 关双, 于亚南, 刘骏, 王思村, 王忠. 医学数字孪生方法及其应用[J]. 协和医学杂志. doi: 10.12290/xhyxzz.2023-0157
引用本文: 陈亚飞, 刘琼, 关双, 于亚南, 刘骏, 王思村, 王忠. 医学数字孪生方法及其应用[J]. 协和医学杂志. doi: 10.12290/xhyxzz.2023-0157
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CHEN Yafei, LIU Qiong, GUAN Shuang, YU Yanan, LIU Jun, WANG Sicun, WANG Zhong. The Method and Application of Digital Twinning in Medicine[J]. Medical Journal of Peking Union Medical College Hospital. doi: 10.12290/xhyxzz.2023-0157
Citation: CHEN Yafei, LIU Qiong, GUAN Shuang, YU Yanan, LIU Jun, WANG Sicun, WANG Zhong. The Method and Application of Digital Twinning in Medicine[J]. Medical Journal of Peking Union Medical College Hospital. doi: 10.12290/xhyxzz.2023-0157
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医学数字孪生方法及其应用

doi: 10.12290/xhyxzz.2023-0157

  • 中国中医科学院中医临床基础医学研究所, 北京 100007

基金项目: 

中国中医科学院科技创新工程（CI2021A04707)；中国中医科学院重大攻关项目(CI2021A05033)

详细信息
    通讯作者:

    王忠, E-mail:zhonw@vip.sina.com

  • 中图分类号: R-05；TP3

The Method and Application of Digital Twinning in Medicine

  • Institute of Basic Clinical Medicine of Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100007, China

Funds: 

China Academy of Chinese Medical Sciences Innovation fund (CI2021A04707)

    摘要
  • 摘要: 随着高通量测序等新兴生物技术的快速发展,多组学、多维度的生物大数据研发模式揭开序幕,同时数学建模、人工智能、云计算、区块链、大数据、物联网和 5G 等技术的快速迭代为数字孪生的发展提供了可能。数字孪生是对物理对象、流程和系统在数字空间的模型映射,在医学领域展现出巨大的发展前景:(1) 为人体器官及系统提供可视化的三维立体构象, 可辅助临床诊断和治疗;(2) 为基因组学、代谢组学、表型组学等数据挖掘提供有血有肉的"骨架";(3) 对于慢病管理、药物开发和临床试验等流程进行系统模拟, 从而推动医学事业的发展。本文通过梳理数字孪生在医学领域中的方法和应用,以期为我国发展医学数字孪生研究提供参考。
    Abstract: With the rapid development of emerging biotechnologies such as high-throughput sequencing, multi-omics and multi-dimensional research models for biological big data have been initiated. Concurrently, the fast-evolving technologies such as mathematical modeling, artificial intelligence, cloud computing, blockchain, big data, the Internet of Things, and 5G have enabled the possibility of developing digital twin. Digital twin is a model mapping of physical objects, processes, and systems in digital space, which has shown great potential in the medical field. On the one hand, digital twin technology can provide visualized 3D structures for human organs and systems to assist diagnosis and treatment. On the other hand, it provides a tangible "skeleton" for data mining in genomics, metabolomics, and phenomics, and can simulate processes for chronic disease management, drug development, and clinical trials, thereby advancing the medical field. This article reviewed the methods and applications of digital twin in the medical field, aiming to provide reference for the development of medical digital twin research in China.
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出版历程
  • 收稿日期:  2023-03-28
  • 网络出版日期:  2023-09-18

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